2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID
- Product Name
- 2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID
- CAS No.
- 262608-88-8
- Chemical Name
- 2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID
- Synonyms
- RARECHEM AL BK 0319;2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID;3-(2-Fluoro-4-(trifluoromethyl)phenyl)acrylic acid;3-[2-Fluoro-4-(trifluoromethyl)phenyl]-2-propenoic acid;(E)-3-2-Fluoro-4-(trifluoromethyl)phenylprop-2-enoic acid;2-Propenoic acid, 3-[2-fluoro-4-(trifluoromethyl)phenyl]-;(E)-3-[2-fluoro-4-(trifluoromethyl)phenyl]-2-propenoic acid;(2Z)-3-[2-fluoro-4-(trifluoromethyl)phenyl]prop-2-enoic acid
- CBNumber
- CB3457490
- Molecular Formula
- C10H6F4O2
- Formula Weight
- 234.15
- MOL File
- Mol file
2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H272May intensify fire; oxidizer
H303May be harmfulif swallowed
- Precautionary statements
-
P221Take any precaution to avoid mixing with combustibles/…
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P403Store in a well-ventilated place.
N-Bromosuccinimide Price
- Product number
- 002441
- Product name
- 2-Fluoro-4-(trifluoromethyl)cinnamic acid
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- PC0783
- Product name
- 2-Fluoro-4-(trifluoromethyl)cinnamicacid
- Purity
- 98%
- Packaging
- 1g
- Price
- $40
- Updated
- 2021/12/16
- Product number
- 007927
- Product name
- 2-Fluoro-4-(trifluoromethyl)cinnamicacid
- Purity
- 99%
- Packaging
- 1g
- Price
- $90
- Updated
- 2021/12/16
- Product number
- 002441
- Product name
- 2-Fluoro-4-(trifluoromethyl)cinnamic acid
- Packaging
- 5g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- PC0783
- Product name
- 2-Fluoro-4-(trifluoromethyl)cinnamicacid
- Purity
- 98%
- Packaging
- 5g
- Price
- $119
- Updated
- 2021/12/16
2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID Chemical Properties,Usage,Production
Synthesis
141-82-2
89763-93-9
262608-88-8
Example 3: General procedure for the synthesis of 3-(2-fluoro-4-(trifluoromethyl)phenyl)acrylic acid from malonic acid and 2-fluoro-4-(trifluoromethyl)benzaldehyde. A mixture of 5.0 g (26.0 mmol) of 2-fluoro-4-(trifluoromethyl)benzaldehyde, 3.10 g (29.8 mmol) of malonic acid, 0.26 g (3.0 mmol) of piperidine, and 15 ml of pyridine was heated to reflux temperature until the release of carbon dioxide ceased (about 3 hours). After completion of the reaction, it was cooled to room temperature and the reaction mixture was poured into a mixture of 300 g of ice and 100 ml of 6N HCl. The precipitate was separated, washed twice sequentially with water and n-heptane and dried. 5.2 g (85% yield) of 3-(2-fluoro-4-(trifluoromethyl)phenyl)acrylic acid was obtained.1H-NMR (400MHz, D6-DMSO): δ= 6.73 (d, J = 16.1Hz, 1H, 2-H), 7.63 (d, 1H, 5'-H), 7.65 (d, J = 16.1Hz, 1H, 3-H), 7.76 (d , 1H, 3'-H), 8.07 (dd, 1H, 6'-H), 12.8 (br, 1H, COOH).
References
[1] Patent: US2005/38091, 2005, A1. Location in patent: Page column 6
[2] Patent: US2005/267179, 2005, A1. Location in patent: Page/Page column 15; 16
[3] Patent: WO2008/26149, 2008, A1. Location in patent: Page/Page column 22-23
2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-FLUORO-4-(TRIFLUOROMETHYL)CINNAMIC ACID Suppliers
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