2-(2-PYRIDYLTHIO)ETHAN-1-OL

Product Name: 2-(2-PYRIDYLTHIO)ETHAN-1-OL
CAS No.: 77555-27-2
Chemical Name: 2-(2-PYRIDYLTHIO)ETHAN-1-OL
Synonyms: 2-(2-PYRIDYTHIO)ETHAN-1-OL;2-(2-PYRIDYLTHIO)ETHAN-1-OL;2-(PYRIDIN-2-YLTHIO)ETHANOL;Ethanol, 2-(2-pyridinylthio)-
CBNumber: CB3458750
Molecular Formula: C7H9NOS
Formula Weight: 155.22
MOL File: 77555-27-2.mol

More

Less

2-(2-PYRIDYLTHIO)ETHAN-1-OL Property

Melting point:: 113-114 °C
Boiling point:: 107 °C
Density: 1.2243 g/cm3
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 14.29±0.10(Predicted)

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: P996428
Product name: 2-(2-Pyridylthio)ethan-1-ol
Packaging: 100mg
Price: $60
Updated: 2021/12/16

AK Scientific

Product number: J96822
Product name: 2-(2-Pyridylthio)ethan-1-ol
Packaging: 250mg
Price: $58
Updated: 2021/12/16

AK Scientific

Product number: Y4071
Product name: 2-(2-Pyridylthio)ethan-1-ol
Packaging: 1g
Price: $193
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0018684
Product name: 2-(2-PYRIDYLTHIO)ETHAN-1-OL
Purity: 95.00%
Packaging: 1G
Price: $757.97
Updated: 2021/12/16

AK Scientific

Product number: Y4071
Product name: 2-(2-Pyridylthio)ethan-1-ol
Packaging: 5g
Price: $925
Updated: 2021/12/16

More

Less

2-(2-PYRIDYLTHIO)ETHAN-1-OL Chemical Properties,Usage,Production

Synthesis

109-04-6

60-24-2

77555-27-2

2-Mercaptoethanol (1.09 g, 13.9 mmol) was dissolved in dry hexamethylphosphoryltriamine (HMPA, 3 mL), and sodium hydride (NaH, 0.40 g, 16.7 mmol) was added batchwise under nitrogen protection over 30 minutes. After addition, the reaction mixture was continued to be stirred for 10 min, followed by dropwise addition of 2-bromopyridine (2.00 g, 12.7 mmol). The reaction mixture was stirred at room temperature for 18 hours, then warmed up to 40 °C and continued stirring for 24 hours. Upon completion of the reaction, the reaction was quenched by slow addition of water (20 mL) and the aqueous phase was extracted with dichloromethane (3 x 15 mL). The organic phases were combined, dried over anhydrous magnesium sulfate (MgSO4), filtered and concentrated under reduced pressure to give a yellow oily crude product (5.53 g). Purification by silica gel column chromatography (eluent: ether/hexane, 4:1) afforded 2-(pyridin-2-ylthio)ethanol (19) as a yellow oil (purity ~95%, 1.54 g, yield ~72%). The product was characterized by the following data: infrared spectrum (νmax, neat, cm?1): 3362 (broad peak), 2929, 2864, 1580, 1557, 1455, 1415, 1283, 1232, 1149, 1045, 1016, 942, 878, 758, 724. 1H NMR (300 MHz, CDCl3): δ 3.31 (t, J = 5.5 Hz, 2H, H2), 3.93 (t, J = 5.5 Hz, 2H, H1), 7.00 (ddd, J = 7.4, 5.0, 1.1 Hz, 1H, H5'), 7.25 (dt, J = 8.1, 1.0 Hz, 1H, H3'), 7.48 (ddd, J = 8.0, 7.4, 1.9 Hz 1H, H4'), 8.35 (ddd, J = 5.0, 1.8, 1.0 Hz, 1H, H6'). 13C NMR (75 MHz, CDCl3): δ 33.9 (C2), 63.2 (C1), 119.9, 122.8 (C3', C5'), 136.4 (C4'), 148.9 (C6'), 158.8 ( C2'). Mass spectra (ESI): m/z 155.8 [M + H]+ (55%), 137.8 (100%). High-resolution mass spectrum (ESI+, MeOH): calculated value C7H10NOS [M + H]+ m/z 156.0483, measured value 156.0534. All spectral data are in agreement with literature reports. The conversion of alcohol 19 was 54% (as determined by 1H NMR spectroscopy) when the reaction time was extended to 25 h under the same reaction conditions.

References

[1] Tetrahedron, 1983, vol. 39, # 24, p. 4153 - 4162
[2] Tetrahedron, 2011, vol. 67, # 2, p. 471 - 485
[3] Diss. S. 60,

2-(2-PYRIDYLTHIO)ETHAN-1-OL Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-(2-PYRIDYLTHIO)ETHAN-1-OL Suppliers

Belgium 1 China 20 France 1 Germany 2 India 1 United Kingdom 3 United States 5 Global 33

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: (5)02557626880
Email: dt3@aikonchem.com
Country: China
ProdList: 15493
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Zhengzhou convergence chemical co., LTD

Tel: 0371-0371-55153829 18003835034
Email: 2853979819@qq.com
Country: China
ProdList: 9998
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Email: 2261760024@qq.com
Country: China
ProdList: 4900
Advantage: 58

Henan Evonik Biotechnology Co. LTD

Tel: 15672878902
Email: hnyingchuang@163.com
Country: China
ProdList: 3905
Advantage: 58

Shanghai Maclean Biochemical Technology Co., LTD

Tel: 021-021-50706066 15221275939
Email: shenlinxing@macklin.cn
Country: China
ProdList: 29784
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Beijing FYF Chemicals Co., Ltd

Tel: 010-57903446 15869909019
Email: 168931144@qq.com
Country: China
ProdList: 4965
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Wuxi Likang Biomedical Technology Co., Ltd

Tel: 15250805028 15250805028;
Email: 649163353@qq.com
Country: China
ProdList: 8001
Advantage: 58

ATK CHEMICAL COMPANY LIMITED

Tel: +undefined-21-51877795
Fax: +86 21 5161 9052/ 5187 7796
Email: ivan@atkchemical.com
Country: China
ProdList: 33024
Advantage: 60

Shanghai Machine Pure Industrial Co., Ltd.

Tel: --
Fax: --
Email: 3245176082@qq.com
Country: CHINA
ProdList: 6800
Advantage: 58

Atomax Chemicals Co., Ltd

Tel: --
Fax: --
Email: info@atomaxchem.com
Country: China
ProdList: 6489
Advantage: 43

77555-27-2, 2-(2-PYRIDYLTHIO)ETHAN-1-OLRelated Search:

2-[(6-METHOXY-3-NITRO-2-PYRIDYL)THIO]PROPANOIC ACID 2-(3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDYLTHIO)ACETIC ACID METHYL 2-[[5-(TRIFLUOROMETHYL)-2-PYRIDYL]SULFONYL]ACETATE 2-[(5-CHLORO-2-PYRIDYL)THIO]ETHAN-1-OL 2-(2-PYRIDYLTHIO)ETHAN-1-OL ETHYL 2-((5-[(4-CHLOROANILINO)CARBONYL]-2-PYRIDINYL)SULFANYL)ACETATE 2-[(3-NITRO-2-PYRIDYL)THIO]ACETIC ACID ETHYL 2-((5-[(4-METHOXYANILINO)CARBONYL]-2-PYRIDINYL)SULFANYL)ACETATE AKOS UB-20191 4-[4-(TERT-BUTYL)PHENYL]-4-OXO-2-([5-(TRIFLUOROMETHYL)-2-PYRIDINYL]SULFANYL)BUTANOIC ACID 2-([5-(TRIFLUOROMETHYL)-2-PYRIDYL]SULFONYL)ETHYL 2,3,3-TRICHLOROACRYLATE ETHYL 2-((5-[(2,4-DIFLUOROANILINO)CARBONYL]-2-PYRIDINYL)SULFANYL)ACETATE METHYL 2-(3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDYLTHIO)ACETATE 2-[(6-CHLORO-2-PYRIDYL)SULFONYL]ETHYL 3-CHLOROBENZOATE 2-[(3-NITRO-2-PYRIDYL)THIO]PROPANOIC ACID 3-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]SULFANYL)DIHYDRO-2,5-FURANDIONE ([5-(TRIFLUOROMETHYL)PYRIDIN-2-YL]THIO)ACETIC ACID (1-OXY-PYRIDIN-2-YLSULFANYL)-ACETIC ACID

2-(PYRIDIN-2-YLTHIO)ETHANOL

2-(2-PYRIDYLTHIO)ETHAN-1-OL

2-(2-PYRIDYTHIO)ETHAN-1-OL

Ethanol, 2-(2-pyridinylthio)-

77555-27-2