ISO-OMPA

Product Name: ISO-OMPA
CAS No.: 513-00-8
Chemical Name: ISO-OMPA
Synonyms: DPDA;ISO-OMPA;Dipropyldiphosphoramide;tetraisopropylpyrophosphamide;TETRAISOPROPYL PYROPHOS-PHORAMIDE;Tetraisopropylpyrophosphoramide,~96%;TETRA[MONOISOPROPYL]-PYROPHOSPHORTETRAMIDE;Oxybis[bis(isopropylamino)phosphine oxide];N,N',N'',N'''-tetraisopropyldiphosphoramide;Diphosphoramide, N,N,N,N-tetrakis(1-methylethyl)-
CBNumber: CB3460656
Molecular Formula: C12H32N4O3P2
Formula Weight: 342.36
MOL File: 513-00-8.mol

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ISO-OMPA Property

Melting point:: 151 °C(Solv: acetone (67-64-1))
Boiling point:: 396.7±25.0 °C(Predicted)
Density: 1.076±0.06 g/cm3(Predicted)
storage temp.: -20°C
pka: 1.22±0.70(Predicted)
form: Solid
color: White to off-white
biological source: synthetic
InChI: 1S/C12H32N4O3P2/c1-9(2)13-20(17,14-10(3)4)19-21(18,15-11(5)6)16-12(7)8/h9-12H,1-8H3,(H2,13,14,17)(H2,15,16,18)
InChIKey: IOIMDJXKIMCMIG-UHFFFAOYSA-N
SMILES: CC(C)NP(=O)(NC(C)C)OP(=O)(NC(C)C)NC(C)C
EPA Substance Registry System: Diphosphoramide, N,N',N'',N'''-tetrakis(1-methylethyl)- (513-00-8)

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Safety

Hazard Codes: T+
Risk Statements: 26/27/28
Safety Statements: 22-36/37/39-45
RIDADR: UN 2811 6.1/PG 1
WGK Germany: 3
Storage Class: 6.1B - Non-combustible acute toxic Cat. 1 and 2
very toxic hazardous materials
Hazard Classifications: Acute Tox. 1 Inhalation
Acute Tox. 2 Dermal
Acute Tox. 2 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T1505
Product name: Tetraisopropyl pyrophosphoramide
Purity: butyrylcholinesterase inhibitor
Packaging: 100mg
Price: $70.5
Updated: 2023/01/07

Sigma-Aldrich

Product number: T1505
Product name: Tetraisopropyl pyrophosphoramide
Purity: butyrylcholinesterase inhibitor
Packaging: 1g
Price: $342
Updated: 2022/05/15

Sigma-Aldrich

Product number: T1505
Product name: Tetraisopropyl pyrophosphoramide
Purity: butyrylcholinesterase inhibitor
Packaging: 250mg
Price: $111
Updated: 2022/05/15

American Custom Chemicals Corporation

Product number: INB0001036
Product name: TETRAISOPROPYL PYROPHOSPHORAMIDE
Purity: 95.00%
Packaging: 100MG
Price: $591.34
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001036
Product name: TETRAISOPROPYL PYROPHOSPHORAMIDE
Purity: 95.00%
Packaging: 250MG
Price: $619.96
Updated: 2021/12/16

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ISO-OMPA Chemical Properties,Usage,Production

Uses

Tetraisopropyl pyrophosphoramide has been used:

as a butyrylcholinesterase inhibitor to determine the proportions of butyrylcholinesterase (BChE) in cat and tiger plasma
to inhibit wild-type BChE in acetylcholinesterase assay
to selectively block the enzymatic activity of AChE

Definition

ChEBI: Diphosphoramide, N,N',N'',N'''-tetrakis(1-methylethyl)- is a phosphoramide.

Biochem/physiol Actions

Selective inhibitor of butyrylcholinesterase

in vivo

Iso-OMPA (0.6-1.9 mg/kg, subcutaneous injection, single dose) enhances soman toxicity in rats but has no effect on mice^[3].

Animal Model:	Mouse and rat^[3]
Dosage:	0.6, 1.9 mg/kg; single dose
Administration:	Subcutaneous injection (s.c.)
Result:	Caused rat plasma CarbE activity to be only slightly inhibited by lower doses and significantly inhibited by higher doses. CarbE activity in mice was not inhibited.

IC 50

BuChE

ISO-OMPA Preparation Products And Raw materials

Raw materials

Preparation Products

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ISO-OMPA Suppliers

China 26 Europe 2 Germany 1 Switzerland 2 United Kingdom 2 United States 4 Global 37

Spectrum Chemical Manufacturing Corp.

Tel: 021-021-021-67601398-809-809-809 15221380277
Fax: 021-57711696
Email: marketing_china@spectrumchemical.com
Country: China
ProdList: 9658
Advantage: 60

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Rechem science Co., Ltd.

Tel: 021-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2962
Advantage: 58

Shanghai SuperLan Chemcial Technique Centre

Tel: 0-2022843681 15618226720
Fax: +86-21-51601218
Email: chaolaichem@foxmail.com
Country: China
ProdList: 10408
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: +86-29-87569262 +86-15003564040
Fax: 029-88380327
Email: 1056@dideu.com
Country: China
ProdList: 3982
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18921922613
Email: hywu@aikonchem.com
Country: China
ProdList: 10708
Advantage: 58

Shanghai Yingxin laboratory equipment Co., Ltd

Tel: 021-021-59178156 15300768757
Email: 359382369@qq.com
Country: China
ProdList: 10674
Advantage: 58

Shaanxi Cuikang Pharmaceutical Technology Co., Ltd

Tel: 18049165724; 13186333400
Email: cuichengbio@163.com
Country: China
ProdList: 4856
Advantage: 58

513-00-8, ISO-OMPARelated Search:

Pyrophosphoric acid ISO-OMPA ISOPENTENYL PYROPHOSPHATE AMMONIUM 200

ISO-OMPA

tetraisopropylpyrophosphamide

Diphosphoramide, N,N,N,N-tetrakis(1-methylethyl)-

iso-OMPA, Tetra(monoisopropyl)pyrophosphortetramide

Dipropyldiphosphoramide

DPDA

Oxybis[bis(isopropylamino)phosphine oxide]

[bis(isopropylamino)phosphoryloxy-(isopropylamino)phosphoryl]-isopropyl-amine

N-[bis(propan-2-ylamino)phosphoryloxy-(propan-2-ylamino)phosphoryl]propan-2-amine

Tetraisopropyl pyrophosphoramide,Tetra(monoisopropyl)pyrophosphortetramide, iso-OMPA

TETRA[MONOISOPROPYL]-PYROPHOSPHORTETRAMIDE

TETRAISOPROPYL PYROPHOS-PHORAMIDE

N,N',N'',N'''-tetraisopropyldiphosphoramide

Tetraisopropylpyrophosphoramide,~96%

Tetraisopropyl pyrophosphoramide butyrylcholinesterase inhibitor

513-00-8

C12H32N4O3P2

Enzyme Inhibitors

Cholinesterase, butyryl

A to C

Biochemicals and Reagents

BioChemical

Enzyme Inhibitors by Enzyme

Enzymes, Inhibitors, and Substrates