Allosteric WNK Kinase Inhibitor ,

Product Name: Allosteric WNK Kinase Inhibitor ,
CAS No.: 2123489-30-3
Chemical Name: Allosteric WNK Kinase Inhibitor ,
Synonyms: WNK-IN-11;WNK-IN-11 ，S0015;WNK-IN-11, 10 mM in DMSO;ALLOSTERIC WNK KINASE INHIBITOR;Allosteric WNK Kinase Inhibitor ,;WNK-IN-11; WNK IN 11; WNKIN11; WNK INHIBITOR 11; WNK INHIBITOR-11;2123489-30-3;(5-Chloro-2-(2-(methylamino)thiazol-4-yl)pyridin-4-yl)(4-(4-chlorobenzyl)piperazin-1-yl)methanone;Methanone, [5-chloro-2-[2-(methylamino)-4-thiazolyl]-4-pyridinyl][4-[(4-chlorophenyl)methyl]-1-piperazinyl]-;Threonine proteases,inhibit,WNKIN11,Serine proteases,Serine endopeptidases,Inhibitor,Ser/Thr Protease,WNK IN 11
CBNumber: CB34664001
Molecular Formula: C21H21Cl2N5OS
Formula Weight: 462.4
MOL File: 2123489-30-3.mol

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Allosteric WNK Kinase Inhibitor , Property

Boiling point:: 641.1±65.0 °C(Predicted)
Density: 1.407±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:10): 0.1 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml
form: A crystalline solid
pka: 5.52±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 29676
Product name: WNK-IN-11
Packaging: 5mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 29676
Product name: WNK-IN-11
Packaging: 10mg
Price: $87
Updated: 2024/03/01

Cayman Chemical

Product number: 29676
Product name: WNK-IN-11
Packaging: 25mg
Price: $190
Updated: 2024/03/01

Cayman Chemical

Product number: 29676
Product name: WNK-IN-11
Packaging: 50mg
Price: $263
Updated: 2024/03/01

AK Scientific

Product number: 5080EL
Product name: Wnk-IN-11
Packaging: 5mg
Price: $152
Updated: 2021/12/16

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Allosteric WNK Kinase Inhibitor , Chemical Properties,Usage,Production

Uses

WNK-IN-11 is an allosteric With-No-Lysine (WNK) kinase inhibitor, with an IC50 of 4 nM for WNK1.

References

[1] Yamada K, et al. Optimization of Allosteric With-No-Lysine (WNK) Kinase Inhibitors and Efficacy in Rodent Hypertension Models. J Med Chem. 2017 Aug 24;60(16):7099-7107. DOI:10.1021/acs.jmedchem.7b00708

Allosteric WNK Kinase Inhibitor , Preparation Products And Raw materials

Raw materials

Preparation Products

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Allosteric WNK Kinase Inhibitor , Suppliers

China 40 India 1 United States 5 Global 46

Sichuan Wei Keqi Biological Technology Co., Ltd.

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Career Henan Chemica Co

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2123489-30-3, Allosteric WNK Kinase Inhibitor ,Related Search:

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ALLOSTERIC WNK KINASE INHIBITOR

Allosteric WNK Kinase Inhibitor ,

WNK-IN-11

WNK-IN-11; WNK IN 11; WNKIN11; WNK INHIBITOR 11; WNK INHIBITOR-11;2123489-30-3

(5-Chloro-2-(2-(methylamino)thiazol-4-yl)pyridin-4-yl)(4-(4-chlorobenzyl)piperazin-1-yl)methanone

Methanone, [5-chloro-2-[2-(methylamino)-4-thiazolyl]-4-pyridinyl][4-[(4-chlorophenyl)methyl]-1-piperazinyl]-

Threonine proteases,inhibit,WNKIN11,Serine proteases,Serine endopeptidases,Inhibitor,Ser/Thr Protease,WNK IN 11

WNK-IN-11, 10 mM in DMSO

WNK-IN-11 ，S0015

2123489-30-3