BAY-850

Product Name: BAY-850
CAS No.: 2099142-76-2
Chemical Name: BAY-850
Synonyms: BAY-850;BAY850;BAY 850;BAY-850, 10 mM in DMSO;Benzamide, N-[(1R)-2-[(cis-4-aminocyclohexyl)amino]-1-[(4-cyanophenyl)methyl]ethyl]-2-chloro-4-methoxy-5-[5-[[[(1R)-1-(4-methylphenyl)ethyl]amino]methyl]-2-furanyl]-
CBNumber: CB34667613
Molecular Formula: C38H44ClN5O3
Formula Weight: 654.24
MOL File: 2099142-76-2.mol

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BAY-850 Property

Boiling point:: 771.2±60.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 62.5 mg/mL (95.53 mM)
form: Solid
pka: 13.14±0.46(Predicted)
color: White to light yellow
Water Solubility: H2O: 2mg/mL, clear

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2748
Product name: BAY-850trihydrochloride
Purity: ≥98%(HPLC)
Packaging: 5MG
Price: $286
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML2748
Product name: BAY-850 trihydrochloride
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $919
Updated: 2024/03/01

Biorbyt Ltd

Product number: orb611273
Product name: BAY-850
Purity: >98%
Packaging: 100mg
Price: $1802
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611273
Product name: BAY-850
Purity: >98%
Packaging: 250mg
Price: $3580.2
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611273
Product name: BAY-850
Purity: >98%
Packaging: 1g
Price: $7136.6
Updated: 2021/12/16

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BAY-850 Chemical Properties,Usage,Production

Biological Activity

BAY-850 is a chemical probe th at targets ATPase family AAA domain-containing protein 2 (ATAD2) bromodomain (BD) with submicromolar affinity (Kd of 84.9 nM by MST and 120 nM by BROMOscan) and high selectivity over all other bromodomains tested (no BROMOscan hits at 10 μM). BAY-850 blocks ATAD2 BD from binding acetylated H4 peptide in cell-free assays (IC50 of 20 nM) and displaces full-length ATAD2 from chromatin in live cells (effctive conc. 1 μM by HTRF). To avoid potential unspecific off-target effects, concentrations above 5 μM are not recommended. BAY-460 is a companion control compound with strongly reduced ATAD2 inhibitory potency (IC50 = 16 μM by cell-based HTRF assay; no activity at 10 μM by BROMOscan).

BAY-850 Preparation Products And Raw materials

Raw materials

Preparation Products

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BAY-850 Suppliers

CHINA 20 United States 3 Global 23

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2099142-76-2, BAY-850Related Search:

BAY-850

BAY850;BAY 850

Benzamide, N-[(1R)-2-[(cis-4-aminocyclohexyl)amino]-1-[(4-cyanophenyl)methyl]ethyl]-2-chloro-4-methoxy-5-[5-[[[(1R)-1-(4-methylphenyl)ethyl]amino]methyl]-2-furanyl]-

BAY-850, 10 mM in DMSO

2099142-76-2

C38H44ClN5O3