ChemicalBook > CAS DataBase List > Gefitinib-based PROTAC 3

Gefitinib-based PROTAC 3

Product Name
Gefitinib-based PROTAC 3
CAS No.
2230821-27-7
Chemical Name
Gefitinib-based PROTAC 3
Synonyms
NTN21277;Gefitinib-PROTAC-3;Gefitinib-based PROTAC 3;NTN21277(Gefitinib-based PROTAC 3);Gefitinib-based PROTAC 3,Epidermal growth factor receptor,inhibit,Inhibitor,Gefitinib based PROTAC 3,HER1,PROTACs,ErbB-1,Gefitinibbased PROTAC 3,EGFR;(2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
CBNumber
CB34667936
Molecular Formula
C47H57ClFN7O8S
Formula Weight
934.52
MOL File
2230821-27-7.mol
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Gefitinib-based PROTAC 3 Property

Boiling point:
1065.6±65.0 °C(Predicted)
Density 
1.300±0.06 g/cm3(Predicted)
storage temp. 
4°C, away from moisture and light
solubility 
DMF: 25 mg/ml; DMF:PBS (pH 7.2) (1:3): 0.25 mg/ml; DMSO: 16 mg/ml; Ethanol: 10 mg/ml
form 
A crystalline solid
pka
14.07±0.40(Predicted)
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28597
Product name
Gefitinib-based PROTAC 3
Packaging
1mg
Price
$25
Updated
2024/03/01
Cayman Chemical
Product number
28597
Product name
Gefitinib-based PROTAC 3
Packaging
25mg
Price
$250
Updated
2024/03/01
Cayman Chemical
Product number
28597
Product name
Gefitinib-based PROTAC 3
Packaging
5mg
Price
$81
Updated
2024/03/01
Cayman Chemical
Product number
28597
Product name
Gefitinib-based PROTAC 3
Packaging
10mg
Price
$138
Updated
2024/03/01
ChemScene
Product number
CS-0087480
Product name
Gefitinib-basedPROTAC3
Purity
99.98%
Packaging
10mg
Price
$200
Updated
2021/12/16
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Gefitinib-based PROTAC 3 Chemical Properties,Usage,Production

Description

Gefitinib-based PROTAC 3 contains an EGFR binding element and a von Hippel-Lindau ligand joined by a linker which induces EGFR degradation.

Uses

Gefitinib-based PROTAC 3 is useful for EGFR proteolysis targeting.

storage

Store at -20°C

Gefitinib-based PROTAC 3 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Gefitinib-based PROTAC 3 manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Gefitinib-based PROTAC 3 2230821-27-7
Price
US $0.00/mg
Min. Order
1mg
Purity
98%min
Supply Ability
50mg
Release date
2021-08-26

2230821-27-7, Gefitinib-based PROTAC 3Related Search:


  • Gefitinib-based PROTAC 3
  • NTN21277
  • NTN21277(Gefitinib-based PROTAC 3)
  • Gefitinib-PROTAC-3
  • Gefitinib-based PROTAC 3,Epidermal growth factor receptor,inhibit,Inhibitor,Gefitinib based PROTAC 3,HER1,PROTACs,ErbB-1,Gefitinibbased PROTAC 3,EGFR
  • (2S,4R)-1-((S)-2-(3-(2-((5-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)pentyl)oxy)ethoxy)propanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
  • 2230821-27-7
  • C47H57ClFN7O8S