TAPI-0

Product Name: TAPI-0
CAS No.: 163958-73-4
Chemical Name: TAPI-0
Synonyms: TAPI;TAPI-0 >=95% (HPLC);N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide;L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-
CBNumber: CB34670622
Molecular Formula: C24H32N4O5
Formula Weight: 456.53
MOL File: 163958-73-4.mol

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TAPI-0 Property

Density: 1.227±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO
form: powder
pka: 9.17±0.20(Predicted)
color: white to off-white

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Safety

RIDADR: UN 2811 6.1 / PGIII

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1292
Product name: TAPI-0
Purity: ≥95% (HPLC)
Packaging: 1MG
Price: $351
Updated: 2023/06/20

TRC

Product number: T731300
Product name: TAPI0
Packaging: 1mg
Price: $270
Updated: 2021/12/16

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TAPI-0 Chemical Properties,Usage,Production

Uses

TAPI 0 is a metalloprotease inhibitor, which inhibits the obligate intracellular human pathogen Chalmydia trachomitis.

Biochem/physiol Actions

TAPI-0 is a metalloproteinase inhibitor with selectivity for TACE (TNF-α converting enzyme/ADAM17; IC50 = 100 nM). TAPI-0 also inhibits of collagenase and gelatinase. Although not specific for TACE, TAPI-0 is extensively used to block TACE-mediated TNF-α shedding.

storage

Store at -20°C

TAPI-0 Preparation Products And Raw materials

Raw materials

Preparation Products

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TAPI-0 Suppliers

China 9 United Kingdom 1 United States 1 USA 1 Global 12

163958-73-4, TAPI-0Related Search:

N-[(2R)-2-[2-(Hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-L-alaninamide

L-Alaninamide, N-[(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methyl-1-oxopentyl]-3-(2-naphthalenyl)-L-alanyl-

TAPI-0 >=95% (HPLC)

TAPI

163958-73-4