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MAT2A inhibitor 1

Product Name
MAT2A inhibitor 1
CAS No.
13299-99-5
Chemical Name
MAT2A inhibitor 1
Synonyms
AG270;AG-270;AG 270;MAT2A inhibitor 1;AG-270(MAT2A inhibitor 1);AG-270;AG270;AG 270;13299-99-5;MAT2A inhibitor 2, 10 mM in DMSO;MAT2A inhibitor 2,inhibit,MAT-2A inhibitor 2,Inhibitor;6-(3-methoxyphenyl)-4-methyl-2-(2-morpholin-4-ylethyl)pyridazin-3-one,hydrochloride;6-(3-Methoxyphenyl)-4-methyl-2-(2-morpholinoethyl)pyridazin-3(2H)-one hydrochloride
CBNumber
CB34672338
Molecular Formula
C18H24ClN3O3
Formula Weight
365.86
MOL File
13299-99-5.mol
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MAT2A inhibitor 1 Property

Melting point:
203-209 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
DMSO : 75 mg/mL (205.00 mM)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb573143
Product name
AG-270 (MAT2A inhibitor 1)
Purity
>98%
Packaging
100mg
Price
$986
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573143
Product name
AG-270 (MAT2A inhibitor 1)
Purity
>98%
Packaging
250mg
Price
$1654.1
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573143
Product name
AG-270 (MAT2A inhibitor 1)
Purity
>98%
Packaging
1g
Price
$3282.7
Updated
2021/12/16
Ambeed
Product number
A1001772
Product name
6-(3-Methoxyphenyl)-4-methyl-2-(2-morpholinoethyl)pyridazin-3(2H)-onehydrochloride
Purity
98%
Packaging
1g
Price
$1313
Updated
2021/12/16
CSNpharm
Product number
CSN23722
Product name
MAT2AInhibitor1
Packaging
100mg
Price
$1320
Updated
2021/12/16
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MAT2A inhibitor 1 Chemical Properties,Usage,Production

Uses

MAT2A inhibitor 2 is an inhibitor of methionine adenosine transferase 2A (MAT2A) with oral activity. MAT2A inhibitor 2 can be used in osteoporosis study[1]

in vivo

MAT2A inhibitor 2 (30, 100 mg/kg, orally, for 6 weeks) can prevent bone loss induced by ovariectomy (OVX) in mice[1].

Animal Model:Ovariectomy (OVX)-induced osteoporosis model in C57/BL mice[1]
Dosage:30, 100 mg/kg
Administration:p.o. for 6 weeks
Result:Attenuated trabecular thickness and osteoclast surface/bone surface ratio (Oc.S/BS).

References

[1] Kang H, et al. Inhibition of MAT2A suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss. FASEB J. 2022 Feb;36(2):e22167. DOI:10.1096/fj.202101205RR

MAT2A inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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MAT2A inhibitor 1 Suppliers

China 40 India 1 United States 3 Global 44
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Wuhan Greatwall chemical Co,.LTD
Tel
400-027-6116 18086000087
Fax
QQ: 2680733325
Email
sales@chemgreatwall.com
Country
China
ProdList
1559
Advantage
55
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
8011
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9126
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
Henan Weituxi Chemical Technology Co., Ltd.
Tel
0371-63284658 18135795563
Fax
QQ:2885349392
Email
2885349392@qq.com
Country
China
ProdList
9992
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58

13299-99-5, MAT2A inhibitor 1Related Search:

TYRPHOSTIN A1

  • MAT2A inhibitor 1
  • AG-270(MAT2A inhibitor 1)
  • 6-(3-Methoxyphenyl)-4-methyl-2-(2-morpholinoethyl)pyridazin-3(2H)-one hydrochloride
  • AG270
  • AG-270
  • AG-270;AG270;AG 270;13299-99-5
  • AG 270
  • 6-(3-methoxyphenyl)-4-methyl-2-(2-morpholin-4-ylethyl)pyridazin-3-one,hydrochloride
  • MAT2A inhibitor 2,inhibit,MAT-2A inhibitor 2,Inhibitor
  • MAT2A inhibitor 2, 10 mM in DMSO
  • 13299-99-5