ChemicalBook > CAS DataBase List > DK419
DK419
- Product Name
- DK419
- CAS No.
- 2102672-22-8
- Chemical Name
- DK419
- Synonyms
- DK419;DK419, 10 mM in DMSO;inhibit,DK419,Wnt,β-catenin,Inhibitor,DK 419,Beta catenin,DK-419;1H-Benzimidazole-7-carboxamide, 5-chloro-2-(trifluoromethyl)-N-[4-(trifluoromethyl)phenyl]-
- CBNumber
- CB34676583
- Molecular Formula
- C16H8ClF6N3O
- Formula Weight
- 407.7
- MOL File
- 2102672-22-8.mol
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DK419 Property
- Boiling point:
- 417.7±45.0 °C(Predicted)
- Density
- 1.611±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO: 83.33 mg/mL (204.39 mM)
- pka
- 7.22±0.10(Predicted)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
ChemScene
- Product number
- CS-0065701
- Product name
- DK419
- Purity
- 99.68%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0065701
- Product name
- DK419
- Purity
- 99.68%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0065701
- Product name
- DK419
- Purity
- 99.68%
- Packaging
- 50mg
- Price
- $1650
- Updated
- 2021/12/16
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DK419 Chemical Properties,Usage,Production
Description
DK419 is a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth. DK419 inhibited Wnt/β-catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally.
DK419 Preparation Products And Raw materials
Raw materials
Preparation Products
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DK419 Suppliers
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