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DK419

Product Name
DK419
CAS No.
2102672-22-8
Chemical Name
DK419
Synonyms
DK419;DK419, 10 mM in DMSO;inhibit,DK419,Wnt,β-catenin,Inhibitor,DK 419,Beta catenin,DK-419;1H-Benzimidazole-7-carboxamide, 5-chloro-2-(trifluoromethyl)-N-[4-(trifluoromethyl)phenyl]-
CBNumber
CB34676583
Molecular Formula
C16H8ClF6N3O
Formula Weight
407.7
MOL File
2102672-22-8.mol
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DK419 Property

Boiling point:
417.7±45.0 °C(Predicted)
Density 
1.611±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO: 83.33 mg/mL (204.39 mM)
pka
7.22±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0065701
Product name
DK419
Purity
99.68%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0065701
Product name
DK419
Purity
99.68%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0065701
Product name
DK419
Purity
99.68%
Packaging
50mg
Price
$1650
Updated
2021/12/16
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DK419 Chemical Properties,Usage,Production

Description

DK419 is a potent inhibitor of Wnt/β-catenin signaling and colorectal cancer growth. DK419 inhibited Wnt/β-catenin signaling, altered cellular oxygen consumption rate and induced production of pAMPK. DK419 inhibited the growth of CRC tumor cells in vitro, had good plasma exposure when dosed orally, and inhibited the growth of patient derived CRC240 tumor explants in mice dosed orally.

DK419 Preparation Products And Raw materials

Raw materials

Preparation Products

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DK419 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

2102672-22-8, DK419Related Search:


  • DK419
  • inhibit,DK419,Wnt,β-catenin,Inhibitor,DK 419,Beta catenin,DK-419
  • 1H-Benzimidazole-7-carboxamide, 5-chloro-2-(trifluoromethyl)-N-[4-(trifluoromethyl)phenyl]-
  • DK419, 10 mM in DMSO
  • 2102672-22-8