2-Bromoindene
- Product Name
- 2-Bromoindene
- CAS No.
- 10485-09-3
- Chemical Name
- 2-Bromoindene
- Synonyms
- ETTD;2-BROMOINDENE;2- indene bromide;2-Bromoindene >2-bromo-1H-indene;2-Bromoindene,99%;2-BroMoindene, 95+%;1H-INDENE, 2-BROMO-;2-Bromoindene ISO 9001：2015 REACH;(2-Bromo-5-methoxy-11-methyl-phenyl)-methano
- CBNumber
- CB3468137
- Molecular Formula
- C9H7Br
- Formula Weight
- 195.06
- MOL File
- 10485-09-3.mol
2-Bromoindene Property
- Melting point:
- 35-37°C
- Boiling point:
- 127 °C / 23mmHg
- Density
- 1.570±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,2-8°C
- form
- powder to crystal
- color
- White to Light yellow to Light orange
- Water Solubility
- Insoluble in water.
- InChI
- InChI=1S/C9H7Br/c10-9-5-7-3-1-2-4-8(7)6-9/h1-5H,6H2
- InChIKey
- CCUYEVNCRQDQRF-UHFFFAOYSA-N
- SMILES
- C1C2=C(C=CC=C2)C=C1Br
- CAS DataBase Reference
- 10485-09-3(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- B3163
- Product name
- 2-Bromoindene
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $66
- Updated
- 2025/07/31
- Product number
- B3163
- Product name
- 2-Bromoindene
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $262
- Updated
- 2025/07/31
- Product number
- B688968
- Product name
- 2-Bromoindene
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR1077
- Product name
- 2-Bromo-1H-indene
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FB02221
- Product name
- 2-Bromoindene
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
2-Bromoindene Chemical Properties,Usage,Production
Chemical Properties
Yellow to pale brown low melting solid
Uses
2-Bromoindene is used as pharmaceutical intermediate.
Synthesis
5400-80-6
10485-09-3
General procedure for the synthesis of 2-bromoindene from 2-bromo-1-indanol: In a 25 mL round-bottomed flask, 250 mg (1.2 mmol) of 2-bromo-1-phenylethanol (1a), 50 mg (20 wt%) of H-β zeolite and 1.0 mL of chlorobenzene were added. The reaction flask was heated in an oil bath at 120 °C for 6 h. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the flask was cooled to room temperature and the reaction mixture was filtered through Wattman filter paper and the filter cake was washed with 10 mL of diethyl ether. The filtrate was concentrated under reduced pressure to remove the solvent. The resulting crude product was purified by column chromatography on silica gel (200-400 mesh) to afford 2-bromoindene (2a, 0.16 g) in 72% yield using hexane as eluent.
References
[1] Tetrahedron Letters, 2014, vol. 55, # 10, p. 1793 - 1795
[2] Patent: US2016/194422, 2016, A1. Location in patent: Paragraph 0129; 0138
[3] Journal of Organic Chemistry, 1982, vol. 47, # 4, p. 705 - 709
[4] Patent: EP2390249, 2011, A2. Location in patent: Page/Page column 20-21
[5] Journal of Medicinal Chemistry, 2006, vol. 49, # 7, p. 2222 - 2231
2-Bromoindene Preparation Products And Raw materials
Raw materials
Preparation Products
2-Bromoindene Suppliers
- Tel
- 03-36680489
- Fax
- 03-3668-0520
- Sales-JP@TCIchemicals.com
- Country
- Japan
- ProdList
- 28387
- Advantage
- 80
View Lastest Price from 2-Bromoindene manufacturers
- Product
- 2-Bromoindene 10485-09-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 30tons/month
- Release date
- 2023-04-07
- Product
- 2-Bromoindene 10485-09-3
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 2-Bromoindene 10485-09-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 20KG
- Release date
- 2018-08-07