METOCLOPRAMIDE-D3

Product Name: METOCLOPRAMIDE-D3
CAS No.: 1216522-89-2
Chemical Name: METOCLOPRAMIDE-D3
Synonyms: METOCLOPRAMIDE-D3;[2H3]-Metoclopramide;4-AMino-5-chloro-N-[2-(diethylaMino)ethyl]-2-(Methoxy-d3)benzaMide;4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(trideuteriomethoxy)benzamide;Metoclopramide D3Q: What is Metoclopramide D3 Q: What is the CAS Number of Metoclopramide D3 Q: What is the storage condition of Metoclopramide D3 Q: What are the applications of Metoclopramide D3
CBNumber: CB3473786
Molecular Formula: C14H19ClD3N3O2
Formula Weight: 302.81
MOL File: Mol file

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METOCLOPRAMIDE-D3 Property

Melting point:: 143-148°C
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
color: White

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28885
Product name: Metoclopramide-d3
Packaging: 500μg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 28885
Product name: Metoclopramide-d3
Packaging: 1mg
Price: $115
Updated: 2024/03/01

TRC

Product number: M338687
Product name: Metoclopramide-d3
Packaging: 5mg
Price: $185
Updated: 2021/12/16

AK Scientific

Product number: 9017CT
Product name: Metoclopramide-d3
Packaging: 1mg
Price: $225
Updated: 2021/12/16

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METOCLOPRAMIDE-D3 Chemical Properties,Usage,Production

Description

Metoclopramide-d₃ is intended for use as an internal standard for the quantification of metoclopramide by GC- or LC-MS. Metoclopramide is an orally bioavailable serotonin (5-HT) receptor 5-HT₃ antagonist with K_i and IC₅₀ values of 995 and 308 nM, respectively, in rat cortical membranes. It is also a dopamine D₂ receptor antagonist (IC₅₀ = 483 nM in rat brain synaptic membranes). Oral administration of metoclopramide inhibits emesis induced by cisplatin and apomorphine in ferrets and dogs with ED₅₀ values of 6.17 and 0.45 mg/kg, respectively. Metoclopramide reversibly inhibits human acetylcholinesterase (AChE) isolated from the caudate nucleus (K_is = 9.3 and 82 μM for competitive and non-competitive inhibition, respectively). Formulations containing metoclopramide have been used as anti-emetic and antipsychotic agents.

Chemical Properties

White Crystalline Solid

Uses

Labelled dopamine D2 receptor antagonist. A labelled substituted benzamide with neuroleptic activity. Antiemetic.

METOCLOPRAMIDE-D3 Preparation Products And Raw materials

Raw materials

Preparation Products

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METOCLOPRAMIDE-D3 Suppliers

Canada 2 China 23 India 3 United States 2 Global 30

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1216522-89-2, METOCLOPRAMIDE-D3Related Search:

4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

METOCLOPRAMIDE-D3

4-AMino-5-chloro-N-[2-(diethylaMino)ethyl]-2-(Methoxy-d3)benzaMide

4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-(trideuteriomethoxy)benzamide

[2H3]-Metoclopramide

Metoclopramide D3Q: What is Metoclopramide D3 Q: What is the CAS Number of Metoclopramide D3 Q: What is the storage condition of Metoclopramide D3 Q: What are the applications of Metoclopramide D3

1216522-89-2

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