ChemicalBook > CAS DataBase List > CRTH2-IN-1
CRTH2-IN-1
- Product Name
- CRTH2-IN-1
- CAS No.
- 926661-54-3
- Chemical Name
- CRTH2-IN-1
- Synonyms
- CRTH2-IN-1;Ramatroban analog;CRTH-2-IN-1,CRTH2 IN 1,CRTH2IN1;Pyrido[1,2-a]indole-10-acetic acid, 7-[[(4-fluorophenyl)sulfonyl]methylamino]-6,7,8,9-tetrahydro-
- CBNumber
- CB34797040
- Molecular Formula
- C21H21FN2O4S
- Formula Weight
- 416.47
- MOL File
- 926661-54-3.mol
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CRTH2-IN-1 Property
- Boiling point:
- 636.5±65.0 °C(Predicted)
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 4.50±0.10(Predicted)
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CRTH2-IN-1 Chemical Properties,Usage,Production
Uses
CRTH2-IN-1 (Ramatroban analog) is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist with an IC50 of 6 nM in a human DP2 binding assay.
IC 50
CYP 2C9: 5 μM (IC50); CYP3A4: 7 μM (IC50); hDP2: 6 nM (IC50); hDP1: 1 μM (IC50)
References
[1] Stearns BA, et al. Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine modelof allergic rhinitis. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4647-51. DOI:10.1016/j.bmcl.2009.06.085
CRTH2-IN-1 Preparation Products And Raw materials
Raw materials
Preparation Products
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CRTH2-IN-1 Suppliers
- Tel
- 15911056312
- liming@bio-fount.com
- Country
- China
- ProdList
- 9729
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- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
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- Tel
- 15002134094
- marketing@targetmol.cn
- Country
- China
- ProdList
- 29423
- Advantage
- 58
- Tel
- +1-781-999-5354;
- support@targetmol.com
- Country
- United States
- ProdList
- 39035
- Advantage
- 58
- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19962
- Advantage
- 58