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CRTH2-IN-1

Product Name
CRTH2-IN-1
CAS No.
926661-54-3
Chemical Name
CRTH2-IN-1
Synonyms
CRTH2-IN-1;Ramatroban analog;CRTH-2-IN-1,CRTH2 IN 1,CRTH2IN1;Pyrido[1,2-a]indole-10-acetic acid, 7-[[(4-fluorophenyl)sulfonyl]methylamino]-6,7,8,9-tetrahydro-
CBNumber
CB34797040
Molecular Formula
C21H21FN2O4S
Formula Weight
416.47
MOL File
926661-54-3.mol
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CRTH2-IN-1 Property

Boiling point:
636.5±65.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
4.50±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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CRTH2-IN-1 Chemical Properties,Usage,Production

Uses

CRTH2-IN-1 (Ramatroban analog) is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist with an IC50 of 6 nM in a human DP2 binding assay.

IC 50

CYP 2C9: 5 μM (IC50); CYP3A4: 7 μM (IC50); hDP2: 6 nM (IC50); hDP1: 1 μM (IC50)

References

[1] Stearns BA, et al. Novel tricyclic antagonists of the prostaglandin D2 receptor DP2 with efficacy in a murine modelof allergic rhinitis. Bioorg Med Chem Lett. 2009 Aug 15;19(16):4647-51. DOI:10.1016/j.bmcl.2009.06.085

CRTH2-IN-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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CRTH2-IN-1 Suppliers

China 2 United States 3 Global 5
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354;
Email
support@targetmol.com
Country
United States
ProdList
39035
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19962
Advantage
58

926661-54-3, CRTH2-IN-1Related Search:


  • CRTH2-IN-1
  • Ramatroban analog
  • Pyrido[1,2-a]indole-10-acetic acid, 7-[[(4-fluorophenyl)sulfonyl]methylamino]-6,7,8,9-tetrahydro-
  • CRTH-2-IN-1,CRTH2 IN 1,CRTH2IN1
  • 926661-54-3