ChemicalBook > CAS DataBase List > LOM612
LOM612
- Product Name
- LOM612
- CAS No.
- 2173232-79-4
- Chemical Name
- LOM612
- Synonyms
- LOM612;LOM-612,LOM612;Naphth[2,3-d]isothiazole-4,9-dione, 3-(dimethylamino)-
- CBNumber
- CB34797080
- Molecular Formula
- C13H10N2O2S
- Formula Weight
- 258.3
- MOL File
- 2173232-79-4.mol
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LOM612 Property
- Boiling point:
- 386.2±42.0 °C(Predicted)
- Density
- 1.436±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMSO : 6 mg/mL (23.23 mM);Water : < 0.1 mg/mL (insoluble)
- form
- Solid
- pka
- 3.04±0.20(Predicted)
- color
- Pink to red
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LOM612 Chemical Properties,Usage,Production
Uses
LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells[1].
References
[1] Cautain B, et al. Discovery of a Novel, Isothiazolonaphthoquinone-Based Small Molecule Activator of FOXO Nuclear-Cytoplasmic Shuttling. PLoS One. 2016 Dec 9;11(12):e0167491. DOI:10.1371/journal.pone.0167491
LOM612 Preparation Products And Raw materials
Raw materials
Preparation Products
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