Methoxycarbonyl-PEG5-t-butyl ester

Product Name: Methoxycarbonyl-PEG5-t-butyl ester
CAS No.: 1807530-04-6
Chemical Name: Methoxycarbonyl-PEG5-t-butyl ester
Synonyms: Boc-PEG5-methyl ester;Methoxycarbonyl-PEG5-t-butyl ester;1-(tert-Butyl) 19-methyl 4,7,10,13,16-pentaoxanonadecanedioate;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) 19-methyl ester
CBNumber: CB34811896
Molecular Formula: C19H36O9
Formula Weight: 408.48
MOL File: 1807530-04-6.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22135
Product name: Methoxycarbonyl-PEG5-t-butylester
Purity: 98%
Packaging: 250mg
Price: $360
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1522
Product name: Methoxycarbonyl-PEG5-t-butyl ester
Packaging: 250mg
Price: $701
Updated: 2021/12/16

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Methoxycarbonyl-PEG5-t-butyl ester Chemical Properties,Usage,Production

Uses

Boc-PEG5-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Boc-PEG5-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Methoxycarbonyl-PEG5-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Methoxycarbonyl-PEG5-t-butyl ester Suppliers

China 6 United Kingdom 1 Global 7

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1807530-04-6, Methoxycarbonyl-PEG5-t-butyl esterRelated Search:

Methoxycarbonyl-PEG5-t-butyl ester

4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) 19-methyl ester

Boc-PEG5-methyl ester

1-(tert-Butyl) 19-methyl 4,7,10,13,16-pentaoxanonadecanedioate

1807530-04-6