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SW203668 (trifluoroacetate salt)

Product Name
SW203668 (trifluoroacetate salt)
CAS No.
2117405-48-6
Chemical Name
SW203668 (trifluoroacetate salt)
Synonyms
SW203668 (trifluoroacetate salt);SW203668 (trifluoroacetate salt),SW-203668 (trifluoroacetate salt);4-(aminophenylmethyl)-N-(6-methoxy-2-benzothiazolyl)-benzamide,trifluoroacetatesalt
CBNumber
CB34815298
Molecular Formula
C24H20F3N3O4S
Formula Weight
503.5
MOL File
2117405-48-6.mol
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SW203668 (trifluoroacetate salt) Property

storage temp. 
Store at -20°C
solubility 
DMF: 20 mg/mL; DMSO: 20 mg/ml; Ethanol: 20 mg/ml; Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/mL
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19379
Product name
SW203668 (trifluoroacetate salt)
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
19379
Product name
SW203668 (trifluoroacetate salt)
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
19379
Product name
SW203668 (trifluoroacetate salt)
Packaging
10mg
Price
$213
Updated
2024/03/01
AK Scientific
Product number
4637EH
Product name
4-[Amino(phenyl)methyl]-N-(6-methoxy-1,3-benzothiazol-2-yl)benzamide;2,2,2-trifluoroaceticacid
Packaging
5mg
Price
$226
Updated
2021/12/16
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SW203668 (trifluoroacetate salt) Chemical Properties,Usage,Production

Description

SW203668 is an irreversible inhibitor of stearoyl-CoA desaturase (IC50 = 54 nM). It is selectively cytotoxic to H2122, H460, HCC44, and HCC95 cell lines that express cytochrome P450 (CYP) isoform CYP4F11 over eight other cancer cell lines that lack CYP4F11 in vitro (IC50s = 22-116 and >10,000 nM, respectively) and ectopic expression of CYP4F11 in SW203668-insensitive H1155 cells results in sensitization to SW203668. In vivo, SW203668 reduces tumor growth rate without reducing sebocyte production in the H2122 wild-type and nonobese diabetic severe combined immunodeficiency (NOD-SCID) mouse xenograft models when administered at doses of 20 and 6 mg/kg, respectively.

SW203668 (trifluoroacetate salt) Preparation Products And Raw materials

Raw materials

Preparation Products

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SW203668 (trifluoroacetate salt) Suppliers

China 5 United States 2 Global 7
BOC Sciences
Tel
16314854226
Email
info@bocsci.com
Country
United States
ProdList
9923
Advantage
65
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19699
Advantage
58

2117405-48-6, SW203668 (trifluoroacetate salt)Related Search:


  • SW203668 (trifluoroacetate salt)
  • SW203668 (trifluoroacetate salt),SW-203668 (trifluoroacetate salt)
  • 4-(aminophenylmethyl)-N-(6-methoxy-2-benzothiazolyl)-benzamide,trifluoroacetatesalt
  • 2117405-48-6