ChemicalBook > CAS DataBase List > N1,N2-Dimethyl-2'-O-methylguanosine
N1,N2-Dimethyl-2'-O-methylguanosine
- Product Name
- N1,N2-Dimethyl-2'-O-methylguanosine
- CAS No.
- 2305416-05-9
- Chemical Name
- N1,N2-Dimethyl-2'-O-methylguanosine
- Synonyms
- N1,N2-Dimethyl-2’-O-methylguanosine;N1,N2-Dimethyl-2'-O-methylguanosine;9-((2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-1-methyl-2-(methylamino)-1,9-dihydro-6H-purin-6-one
- CBNumber
- CB34842155
- Molecular Formula
- C13H19N5O5
- Formula Weight
- 325.32
- MOL File
- 2305416-05-9.mol
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N1,N2-Dimethyl-2'-O-methylguanosine Property
- Boiling point:
- 643.9±65.0 °C(Predicted)
- Density
- 1.67±0.1 g/cm3(Predicted)
- pka
- 13.20±0.70(Predicted)
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N1,N2-Dimethyl-2'-O-methylguanosine Chemical Properties,Usage,Production
Uses
N1,N2-Dimethyl-2’-O-methylguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
References
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51. DOI:10.1073/pnas.0631696100
N1,N2-Dimethyl-2'-O-methylguanosine Preparation Products And Raw materials
Raw materials
Preparation Products
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2305416-05-9, N1,N2-Dimethyl-2'-O-methylguanosineRelated Search:
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