AP1867

Product Name: AP1867
CAS No.: 195514-23-9
Chemical Name: AP1867
Synonyms: AP1867;dTAG acid;AP-1867,AP1867;2-(3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid;(1R)-1-[3-(Carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl (2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate;({3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]hexahydropyridin-2-yl]carbonyl}oxy)propyl]phenyl}oxy)acetic acid;2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[3-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-
CBNumber: CB34844467
Molecular Formula: C38H47NO11
Formula Weight: 693.78
MOL File: 195514-23-9.mol

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AP1867 Property

Boiling point:: 814.2±65.0 °C(Predicted)
Density: 1.214±0.06 g/cm3(Predicted)
storage temp.: -20°C, protect from light
solubility: DMSO : ≥ 125 mg/mL (180.17 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 3.14±0.10(Predicted)
color: Light yellow to yellow
InChIKey: XCCRAOPQCACRFC-OIFRRMEBSA-N
SMILES: N1(C(=O)[C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)CCCC[C@H]1C(O[C@@H](C1=CC=CC(OCC(O)=O)=C1)CCC1=CC=C(OC)C(OC)=C1)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0085366
Product name: AP1867
Purity: 98.46%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

ChemScene

Product number: CS-0085366
Product name: AP1867
Purity: 98.46%
Packaging: 10mg
Price: $750
Updated: 2021/12/16

ChemScene

Product number: CS-0085366
Product name: AP1867
Purity: 98.46%
Packaging: 50mg
Price: $2250
Updated: 2021/12/16

ChemScene

Product number: CS-0085366
Product name: AP1867
Purity: 98.46%
Packaging: 100mg
Price: $3350
Updated: 2021/12/16

DC Chemicals

Product number: DC20078
Product name: AP1867
Purity: >98%
Packaging: 100mg
Price: $1100
Updated: 2021/12/16

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AP1867 Chemical Properties,Usage,Production

Uses

AP1867 is a synthetic FKBP12F36V-directed ligand[1].

References

[1] Nabet B, et al. The dTAG system for immediate and target-specific protein degradation. Nat Chem Biol. 2018 May;14(5):431-441. DOI:10.1038/s41589-018-0021-8
[2] Koide K, et al. A synthetic library of cell-permeable molecules. J Am Chem Soc. 2001 Jan 24;123(3):398-408. DOI:10.1021/ja0023377

AP1867 Preparation Products And Raw materials

Raw materials

Preparation Products

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AP1867 Suppliers

China 49 United States 4 Global 53

Shanghai Jiyi Biological Technology Co., LTD

Tel: 021-54135696 18516235431
Fax: 50815371
Email: shgegenetech@163.com
Country: China
ProdList: 469
Advantage: 55

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070 13770331960
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16027
Advantage: 64

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4817
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 86249
Advantage: 60

NanJing Xienuo bio Co.,Ltd.

Tel: 025-84112752 13805181430
Fax: +86-25-84846489
Email: 154301870@qq.com
Country: China
ProdList: 989
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8000
Advantage: 62

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28772
Advantage: 58

SuZhou Medinoah Co.,LTD.

Tel: 0512-69561983 13914027025
Fax: 0512-69561982
Email: zhang_q@medinoah.com
Country: China
ProdList: 3893
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195514-23-9, AP1867Related Search:

AP1867

2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-, (1R)-1-[3-(carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-

AP-1867,AP1867

2-(3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetic acid

dTAG acid

({3-[(1R)-3-(3,4-dimethoxyphenyl)-1-({[(2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]hexahydropyridin-2-yl]carbonyl}oxy)propyl]phenyl}oxy)acetic acid

(1R)-1-[3-(Carboxymethoxy)phenyl]-3-(3,4-dimethoxyphenyl)propyl (2S)-1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)butyl]-2-piperidinecarboxylate

195514-23-9