ChemicalBook > CAS DataBase List > Etrasimod arginine
Etrasimod arginine
- Product Name
- Etrasimod arginine
- CAS No.
- 1206123-97-8
- Chemical Name
- Etrasimod arginine
- Synonyms
- Yiqumod arginine;APD334 L-Arginine;Etrasimod arginine;Etrasimod L-Arginine;Itraconazole Arginate;L-Arginine salt of (R)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid
- CBNumber
- CB34848238
- Molecular Formula
- C32H40F3N5O5
- Formula Weight
- 631.7
- MOL File
- 1206123-97-8.mol
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Etrasimod arginine Property
- storage temp.
- -10 to -25°C
- solubility
- DMSO: 2mg/mL, clear (Warmed)
- form
- powder
- color
- white to beige
- InChIKey
- GVPVVOSNDUAUKM-MRIOYIRHNA-N
- SMILES
- C([C@H](N)C(=O)O)CCNC(N)=N.C([C@H]1CCC2C3=CC(OCC4C=CC(C5CCCC5)=C(C(F)(F)F)C=4)=CC=C3NC1=2)C(=O)O |&1:1,13,r|
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Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
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Etrasimod arginine Chemical Properties,Usage,Production
Uses
Etrasimod arginine is an orally available S1P receptor modulator that is a potent full agonist of the S1P1 receptor and has partial agonist activity at S1P4. Etrasimod arginine reduces inflammation in a CD4+CD45RBhigh T cell-transferred mouse colitis model[1].
Biological Activity
Etrasimod arginine is an orally available, potent, and selective agonist of Sphingosine-1-Phosphate Receptors 1 (S1PR1). Also, it acts as a partial agonist of S1PR4,5. Etrasimod arginine induces reductions in lymphocyte counts in mice. It is acting as immunosuppressive agents.
References
[1] Etrasimod arginine. Sphingosine-1-phosphate receptor 1 (S1P1 receptor) agonist, Treatment of ulcerative colitis
Etrasimod arginine Preparation Products And Raw materials
Raw materials
Preparation Products
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Etrasimod arginine Suppliers
- Tel
- 81525288 18086100502
- Fax
- 027-86589137
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- China
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- 370
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- 8555
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- +86-571-85224801; 13588483690
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- 0571-85241599
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- 17314186806
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- 0530-+86-530-529 6766，+86-15666160102 15666160102
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- 18201884268
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View Lastest Price from Etrasimod arginine manufacturers
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
- Product
- Etrasimod arginine 1206123-97-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 50kg/Month
- Release date
- 2024-06-28
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
- Product
- Etrasimod arginine. 1206123-97-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 50kg/Month
- Release date
- 2025-01-07