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Gepotidacin mesylate

Product Name
Gepotidacin mesylate
CAS No.
1624306-20-2
Chemical Name
Gepotidacin mesylate
Synonyms
Gepotidacin mesylate dihydrate;(R)-2-((4-(((3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl)amino)piperidin-1-yl)methyl)-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione methanesulfonate dihydrate;mesylate hydrate;Gepotidacin mesylate;Gepotidacin Mesylate Dihydrate INN;Gepotidacin mesylate,PhEur/USP(DMF);8H-2a,5,8a-triazaacenaphthylene-3,8-dione methanesulfonate dihydrate
CBNumber
CB34848243
Molecular Formula
C25H32N6O6S
Formula Weight
544.63
MOL File
1624306-20-2.mol
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Gepotidacin mesylate Property

form 
Solid
color 
Off-white to light yellow
InChIKey
ISCBDQIDBOQJCT-JHTMQSDJNA-N
SMILES
S(O)(=O)(=O)C.C(N1CCC(NCC2=NC=C3OCCCC3=C2)CC1)[C@@H]1CN2C(C=CC3N=CC(=O)N1C2=3)=O |&1:24,r|
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ACHEMBLOCK
Product number
AD265334
Product name
Gepotidacin mesylate dihydrate
Purity
98%
Packaging
5MG
Price
$415
Updated
2026/05/27
ACHEMBLOCK
Product number
AD265334
Product name
Gepotidacin mesylate dihydrate
Purity
98%
Packaging
25MG
Price
$1425
Updated
2026/05/27
DC Chemicals
Product number
DC66602
Product name
Gepotidacin mesylate
Purity
>98%
Packaging
100mg
Price
$750
Updated
2026/05/24
DC Chemicals
Product number
DC66602
Product name
Gepotidacin mesylate
Purity
>98%
Packaging
250mg
Price
$1350
Updated
2026/05/24
DC Chemicals
Product number
DC66602
Product name
Gepotidacin mesylate
Purity
>98%
Packaging
1g
Price
$2600
Updated
2026/05/24
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Gepotidacin mesylate Chemical Properties,Usage,Production

Uses

Gepotidacin mesylate hydrate is an orally active triazaacenaphthylene antibiotic and bacterial type II topoisomerase inhibitor. Gepotidacin mesylate hydrate inhibits bacterial DNA replication by blocking topoisomerase enzymes. Gepotidacin mesylate hydrate selectively inhibits topoisomerase IV and the B subunit of DNA gyrase[1][2].

References

[1] Gibson EG, et al. Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase. ACS Infect Dis. 2019 Apr 12;5(4):570-581. DOI:10.1021/acsinfecdis.8b00315
[2] Watkins RR, et al. Gepotidacin: a novel, oral, 'first-in-class' triazaacenaphthylene antibiotic for the treatment of uncomplicated urinary tract infections and urogenital gonorrhoea. J Antimicrob Chemother. 2023 May 3;78(5):1137-1142. DOI:10.1093/jac/dkad060

Gepotidacin mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Gepotidacin mesylate Suppliers

Shenzhen HwaGen Pharmaceutical Co.,Ltd
Tel
Q:3003761227 17722620669
Email
liangcong.yi@rafflespt.com
Country
China
ProdList
267
Advantage
58
Chengdu Miracle Pharmaceutical Co., Ltd.
Tel
028-86136736 19130631884
Fax
028-85265615
Email
sales@mic-pharma.com
Country
China
ProdList
345
Advantage
56
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4845
Advantage
55
Cangzhou Enke Pharma-tech Co., Ltd.
Tel
0317-5296180 15533709196
Email
enkepharma@126.com;sale@enkepharma.com
Country
China
ProdList
2426
Advantage
55
Shanghai Yunpun industrial Co.,Ltd
Tel
21-61726900 15202122459
Fax
+86-21-60277507
Email
sales@yunpun.com
Country
China
ProdList
493
Advantage
58
Shanghai Chaolan Chemical Technology Center
Tel
QQ:65489617 19372819560
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9627
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32466
Advantage
58
Hunan ravel Biotechnology Co.,Ltd
Tel
18502762003
Email
435918333@qq.com
Country
China
ProdList
1895
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310 15002144251
Email
marketing@tsbiochem.com
Country
China
ProdList
24955
Advantage
58
Cangzhou Kangrui Medical Technology Co., LTD
Tel
18632776803
Email
cangzhoukangrui@126.com;355803330@qq.com
Country
China
ProdList
645
Advantage
58
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View Lastest Price from Gepotidacin mesylate manufacturers

BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Gepotidacin Mesylate Dihydrate 1624306-20-2
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2025-09-09
Guangzhou Weiaokang Pharmaceutical Technology Co., Ltd
Product
Gepotidacin mesylate,PhEur/USP(DMF) 1624306-20-2
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
500kg
Release date
2025-08-05

1624306-20-2, Gepotidacin mesylateRelated Search:


  • Gepotidacin mesylate
  • Gepotidacin mesylate,PhEur/USP(DMF)
  • 8H-2a,5,8a-triazaacenaphthylene-3,8-dione methanesulfonate dihydrate
  • mesylate hydrate
  • Gepotidacin Mesylate Dihydrate INN
  • (R)-2-((4-(((3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl)amino)piperidin-1-yl)methyl)-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione methanesulfonate dihydrate
  • Gepotidacin mesylate dihydrate
  • 1624306-20-2
  • C24H28N6O3CH4SO32H2O