Gepotidacin mesylate
- Product Name
- Gepotidacin mesylate
- CAS No.
- 1624306-20-2
- Chemical Name
- Gepotidacin mesylate
- Synonyms
- Gepotidacin mesylate;Gepotidacin mesylate dihydrate;Gepotidacin mesylate，PhEur/USP(DMF);8H-2a,5,8a-triazaacenaphthylene-3,8-dione methanesulfonate dihydrate;(R)-2-((4-(((3,4-dihydro-2H-pyrano[2,3-c]pyridin-6-yl)methyl)amino)piperidin-1-yl)methyl)-1,2-dihydro-3H,8H-2a,5,8a-triazaacenaphthylene-3,8-dione methanesulfonate dihydrate
- CBNumber
- CB34848243
- Molecular Formula
- C25H32N6O6S
- Formula Weight
- 544.63
- MOL File
- 1624306-20-2.mol
Gepotidacin mesylate Property
- form
- Solid
- color
- Off-white to light yellow
- InChIKey
- ISCBDQIDBOQJCT-JHTMQSDJNA-N
- SMILES
- S(O)(=O)(=O)C.C(N1CCC(NCC2=NC=C3OCCCC3=C2)CC1)[C@@H]1CN2C(C=CC3N=CC(=O)N1C2=3)=O |&1:24,r|
Gepotidacin mesylate Chemical Properties,Usage,Production
Uses
Gepotidacin mesylate hydrate is an orally active triazaacenaphthylene antibiotic and bacterial type II topoisomerase inhibitor. Gepotidacin mesylate hydrate inhibits bacterial DNA replication by blocking topoisomerase enzymes. Gepotidacin mesylate hydrate selectively inhibits topoisomerase IV and the B subunit of DNA gyrase[1][2].
References
[1] Gibson EG, et al. Mechanistic and Structural Basis for the Actions of the Antibacterial Gepotidacin against Staphylococcus aureus Gyrase. ACS Infect Dis. 2019 Apr 12;5(4):570-581. DOI:10.1021/acsinfecdis.8b00315
[2] Watkins RR, et al. Gepotidacin: a novel, oral, 'first-in-class' triazaacenaphthylene antibiotic for the treatment of uncomplicated urinary tract infections and urogenital gonorrhoea. J Antimicrob Chemother. 2023 May 3;78(5):1137-1142. DOI:10.1093/jac/dkad060
Gepotidacin mesylate Preparation Products And Raw materials
Raw materials
Preparation Products
Gepotidacin mesylate Suppliers
- Tel
- 18927334162 18927334162;17722620669
- sales1@rafflespt.com
- Country
- China
- ProdList
- 293
- Advantage
- 58
- Tel
- 028-86136736 19130631884
- Fax
- 028-85265615
- sales@mic-pharma.com
- Country
- China
- ProdList
- 339
- Advantage
- 56
- Tel
- 021-52996696，15000506266 15000506266
- Fax
- +86-21-52996696
- Country
- China
- ProdList
- 4797
- Advantage
- 55
- Tel
- 0317-5296180 15533709196
- enkepharma@126.com;sale@enkepharma.com
- Country
- China
- ProdList
- 2305
- Advantage
- 55
- Tel
- 21-61726900 15202122459
- Fax
- +86-21-60277507
- sales@yunpun.com
- Country
- China
- ProdList
- 500
- Advantage
- 58
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9498
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32470
- Advantage
- 58
- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24963
- Advantage
- 58
- Tel
- 18632776803
- cangzhoukangrui@126.com;355803330@qq.com
- Country
- China
- ProdList
- 639
- Advantage
- 58
- Tel
- 13720134139 086-15871494362 13720134139
- orders@jknbiochem.com
- Country
- China
- ProdList
- 6784
- Advantage
- 58
View Lastest Price from Gepotidacin mesylate manufacturers
- Product
- Gepotidacin Mesylate Dihydrate 1624306-20-2
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 100kg/Month
- Release date
- 2025-09-09
- Product
- Gepotidacin mesylate，PhEur/USP(DMF) 1624306-20-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 500kg
- Release date
- 2025-08-05