ChemicalBook > CAS DataBase List > 4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE

4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE

Product Name
4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE
CAS No.
214697-26-4
Chemical Name
4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE
Synonyms
ABT 702 dihydrochlor;ABT 702 DIHYDROCHLORIDE;Adenosine Kinase Inhibitor;5-(3-broMophenyl)-7-(6-Morpholinopyridin-3-yl)pyrido[2,3-d]pyriMidin-4-aMine;4-Amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidine;5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-pyrido[2,3-d]pyrimidin-4-amine;Pyrido[2,3-d]pyrimidin-4-amine, 5-(3-bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-;5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine;5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-aminedihydrochloride;4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE
CBNumber
CB3485536
Molecular Formula
C22H19BrN6O
Formula Weight
463.33
MOL File
214697-26-4.mol
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4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE Property

Melting point:
227-245 °C(lit.)
storage temp. 
Desiccate at RT
solubility 
DMSO: 24 mg/mL
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
254504
Product name
ABT 702 dihydrochloride
Packaging
10mg
Price
$616
Updated
2021/12/16
Axon Medchem
Product number
Axon2289
Product name
ABT702
Purity
99%
Packaging
5mg
Price
$132
Updated
2021/12/16
Axon Medchem
Product number
Axon2289
Product name
ABT702
Purity
99%
Packaging
2x5mg
Price
$198
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008635
Product name
5-(3-BROMOPHENYL)-7-[6-(4-MORPHOLINYL)-3-PYRIDINYL]-PYRIDO[2,3-D]PYRIMIDIN-4-AMINE
Purity
95.00%
Packaging
5MG
Price
$504.72
Updated
2021/12/16
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4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE Chemical Properties,Usage,Production

Uses

ABT 702 Dihydrochloride is employed in the assay for quantitative high-?throughput screening of anti-?hepatitis C virus compounds.

Biological Activity

Potent non-nucleoside adenosine kinase inhibitor (IC 50 = 1.7 nM), selective over other sites of adenosine interaction (A 1 , A 2A and A 3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in animal models of pain and inflammation.

4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE Suppliers

Axon Medchem BV
Tel
--
Fax
--
Email
info@axonmedchem.com
Country
The Netherlands
ProdList
477
Advantage
30

214697-26-4, 4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDERelated Search:


  • 5-(3-BROMOPHENYL)-7-[6-(4-MORPHOLINYL-PYRIDIN-3-YL)-3-PYRIDO[2,3-D]PYRIMIDIN-4-AMINE] DIHYDROCHLORIDE
  • 4-AMINO-5-(3-BROMOPHENYL)-7-(6-MORPHOLINO-PYRIDIN-3-YL)PYRIDO[2,3-D]PYRIMIDINE DIHYDROCHLORIDE
  • ABT 702 DIHYDROCHLORIDE
  • 5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-pyrido[2,3-d]pyrimidin-4-amine
  • 4-Amino-5-(3-bromophenyl)-7-(6-morpholinopyridin-3-yl)pyrido[2,3-d]pyrimidine
  • 5-(3-Bromophenyl)-7-[6-(4-morpholinyl)-3-pyrido[2,3-d]byrimidin-4-aminedihydrochloride
  • 5-(3-broMophenyl)-7-(6-Morpholinopyridin-3-yl)pyrido[2,3-d]pyriMidin-4-aMine
  • Adenosine Kinase Inhibitor
  • 5-(3-Bromo-phenyl)-7-(6-morpholin-4-yl-pyridin-3-yl)-pyrido[2,3-d]pyrimidin-4-ylamine
  • Pyrido[2,3-d]pyrimidin-4-amine, 5-(3-bromophenyl)-7-[6-(4-morpholinyl)-3-pyridinyl]-
  • ABT 702 dihydrochlor
  • 214697-26-4
  • C22H19BrN6O
  • C22H19N6OBr2HCl
  • C22H19BrN6O2HCl
  • Adenosine receptor