UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)

Product Name: UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)
CAS No.: 342878-90-4
Chemical Name: UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)
Synonyms: URP, HUMAN, RAT;URP (HUMAN, MOUSE, RAT);UIIB (HUMAN, MOUSE, RAT);UROTENSIN II-RELATED PEPTIDE;M.W. 1017.23 C49H64N10O10S2;ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL;UROTENSIN IIB (HUMAN, MOUSE, RAT);H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH;UROTENSIN II RELATED PEPTIDE, HUMAN, RAT;ACFWKYCV( Disulfide bridge between 2 - 7)
CBNumber: CB3489514
Molecular Formula: C49H64N10O10S2
Formula Weight: 1017.22
MOL File: 342878-90-4.mol

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UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) Property

Boiling point:: 1424.2±65.0 °C(Predicted)
Density: 1.39±0.1 g/cm3(Predicted)
storage temp.: Desiccate at -20°C
solubility: Soluble to 1 mg/ml in 5% acetonitrile / sterile water
form: Powder
pka: 3.60±0.10(Predicted)
color: White to off-white
Sequence: Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge:Cys2-Cys7)

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Hazard and Precautionary Statements (GHS)

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UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) Chemical Properties,Usage,Production

Description

Potent endogenous agonist for the urotensin-II (UT) receptor. Binds with high affinity and potently activates recombinant rat and human UT receptors (EC50 values are 0.55 and 4.8 nM respectively). Produces hypotensive effects following systemic administration in rats.

Uses

Urotensin II-related peptide is a human urotensin II anague. Urotensin II-related peptide has high affinity for the UT receptor[1][2].

References

[1] Lescot E, et al. Nonpeptide Urotensin-II receptor agonists and antagonists: Review and structure–activity relationships Peptides. 2008 May;29(5):680-90. DOI:10.1016/j.peptides.2007.09.019
[2] Labarrère P, et al. Structure-activity relationships of human urotensin II and related analogues on rat aortic ring contraction. J Enzyme Inhib Med Chem. 2003 Apr;18(2):77-88. DOI:10.1080/1475636031000093507

UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

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UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) Suppliers

China 34 Europe 1 France 1 Germany 2 Japan 1 United Kingdom 1 United States 4 Global 44

3B Pharmachem (Wuhan) International Co.,Ltd.

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342878-90-4, UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)Related Search:

ASP-PEN-PHE-TRP-LYS-TYR-CYS-VAL (Pyr1)-Urotensin II urotensin II UROTENSIN II (HUMAN) UROTENSIN I ANTI-UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) ([125I]-TYR)-UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT) UROTENSIN-II H-GLU-THR-PRO-ASP-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH, CYS5,10, CYCLIC UROTENSIN II, RAT

M.W. 1017.23 C49H64N10O10S2

Ala-Cys-Phe-Trp-Lys-Tyr-Cys-Val (Disulfide bridge Cys2-Cys7)

UIIB (huMan, Mouse, rat), Urotensin IIB (huMan, Mouse, rat), URP (huMan, Mouse, rat)

ACFWKYCV( Disulfide bridge between 2 - 7)

ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL

H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH

H-ALA-CYS-PHE-TRP-LYS-TYR-CYS-VAL-OH, (DISULFIDE BOND)

UIIB (HUMAN, MOUSE, RAT)

UROTENSIN IIB (HUMAN, MOUSE, RAT)

UROTENSIN II-RELATED PEPTIDE

UROTENSIN II-RELATED PEPTIDE (HUMAN, MOUSE, RAT)

UROTENSIN II RELATED PEPTIDE, HUMAN, RAT

UROTENSIN II-RELATED PEPTIDE (HUMAN, RAT) (MOUSE)

URP (HUMAN, MOUSE, RAT)

URP, HUMAN, RAT

L-Valine, L-alanyl-L-cysteinyl-L-phenylalanyl-L-tryptophyl-L-lysyl-L-tyrosyl-L-cysteinyl-, cyclic (2→7)-disulfide

342878-90-4

C49H64N10O10S2

Urotensin receptor