ChemicalBook > CAS DataBase List > Fmoc-Gly-Gly-Phe-OH

Fmoc-Gly-Gly-Phe-OH

Product Name
Fmoc-Gly-Gly-Phe-OH
CAS No.
160036-44-2
Chemical Name
Fmoc-Gly-Gly-Phe-OH
Synonyms
Fmoc-GGF;Fmoc-Gly-Gly-L-Phe;Fomc-Gly-Gly-Phe-OH;Fmoc-Gly-Gly-Phe-OH;N-Fmoc-glycyl-glycyl-L-phenylalanine;(((9H-fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanine;L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-;(S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9-trioxo-2-oxa-4,7,10-triazadodecan-12-oic acid;(2S)-2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetamido}-3-phenylpropanoic acid;(2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoic acid
CBNumber
CB34921429
Molecular Formula
C28H27N3O6
Formula Weight
501.53
MOL File
160036-44-2.mol
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Fmoc-Gly-Gly-Phe-OH Property

Boiling point:
852.2±65.0 °C(Predicted)
Density 
1.315±0.06 g/cm3(Predicted)
pka
3.50±0.10(Predicted)
form 
Solid
color 
White to off-white
InChIKey
UFGUUZVZUIXKQZ-DEOSSOPVSA-N
SMILES
C(O)(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0141749
Product name
Fmoc-Gly-Gly-Phe-OH
Packaging
500mg
Price
$300
Updated
2021/12/16
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Fmoc-Gly-Gly-Phe-OH Chemical Properties,Usage,Production

Description

Fmoc-Gly-Gly-Phe-OH is an Fmoc-protected glycine derivative with a carboxylate group at the α position and an amide group at the β position. It is a white solid that can be synthesized by the reaction of ethyl glycine with glyoxylic acid in a solvent such as chloroform. This compound can be used for proteomic research and solid-phase peptide synthesis technology. It has been used to study the binding of oxytocin to its receptor, which is important in regulating uterine contractions during labor.

Uses

Fmoc-Gly-Gly-Phe-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

IC 50

Cleavable Linker

storage

-20℃ 3 years powder; -80℃ 2 years in solvent

Fmoc-Gly-Gly-Phe-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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160036-44-2, Fmoc-Gly-Gly-Phe-OHRelated Search:


  • (2S)-2-{2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]acetamido}-3-phenylpropanoic acid
  • N-Fmoc-glycyl-glycyl-L-phenylalanine
  • Fmoc-GGF
  • L-Phenylalanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]glycylglycyl-
  • Fmoc-Gly-Gly-Phe-OH
  • Fmoc-Gly-Gly-L-Phe
  • (S)-11-Benzyl-1-(9H-fluoren-9-yl)-3,6,9-trioxo-2-oxa-4,7,10-triazadodecan-12-oic acid
  • (((9H-fluoren-9-yl)methoxy)carbonyl)glycylglycyl-L-phenylalanine
  • (2S)-2-[[2-[[2-(9H-fluoren-9-ylmethoxycarbonylamino)acetyl]amino]acetyl]amino]-3-phenylpropanoic acid
  • Fomc-Gly-Gly-Phe-OH
  • 160036-44-2
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  • ADCs Linkers
  • ADC LINKER