(-)-BICUCULLINE METHBROMIDE

Product Name: (-)-BICUCULLINE METHBROMIDE
CAS No.: 66016-70-4
Chemical Name: (-)-BICUCULLINE METHBROMIDE
Synonyms: (-)-BICUCULLINE METHBROMIDE;1(S),9(R)-(-)-Bicuculline methbromide;1(s),9(r)-(-)-bicuculline methobromide;(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one;[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide;(5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1)
CBNumber: CB3496965
Molecular Formula: C21H20NO6.Br
Formula Weight: 462.294
MOL File: 66016-70-4.mol

More

Less

(-)-BICUCULLINE METHBROMIDE Property

storage temp.: 2-8°C
solubility: aqueous base: unstable
form: solid
color: white
Water Solubility: Soluble to 50 mM in water

More

Less

Safety

Hazard Codes: T+,N
Risk Statements: 24-28-50
Safety Statements: 24/25-61-45-36/37-28
RIDADR: UN 1544 6.1/PG 2
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B7561
Product name: 1(S),9(R)-(?)-Bicuculline methbromide
Purity: ≥98% (HPLC), solid
Packaging: 25mg
Price: $173
Updated: 2024/03/01

Sigma-Aldrich

Product number: B7561
Product name: 1(S),9(R)-(?)-Bicuculline methbromide
Purity: ≥98% (HPLC), solid
Packaging: 125mg
Price: $724
Updated: 2024/03/01

More

Less

(-)-BICUCULLINE METHBROMIDE Chemical Properties,Usage,Production

Uses

1(S),9(R)-(-)-Bicuculline methbromide has been used:

as a γ-aminobutyric acid (GABAA) receptor A antagonist: in cortical neuron culture
in artificial cerebrospinal fluid (ACSF) formature dentate granule neurons
in hypothalamic explant cultures

Biochem/physiol Actions

1(S),9(R)-(?)-Bicuculline methbromide is a GABAA receptor antagonist, which blocks Ca2+-activated potassium (SK) channels. It is the water-soluble derivative of (+)-bicuculline.

storage

Store at RT

(-)-BICUCULLINE METHBROMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(-)-BICUCULLINE METHBROMIDE Suppliers

China 3 Switzerland 1 United States 2 Global 6

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 4030
Advantage: 58

Aladdin Scientific

Tel: +1-833-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52927
Advantage: 58

66016-70-4, (-)-BICUCULLINE METHBROMIDERelated Search:

(6R)-6-[(5S)-6,6-dimethyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-6-ium-5-yl]-6H-furo[3,4-g][1,3]benzodioxol-8-one

(-)-BICUCULLINE METHBROMIDE

[r-(r*,s*)]-5-(6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquindinium bromide

1(s),9(r)-(-)-bicuculline methobromide

(5S)-5-[(6R)-6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium bromide (1:1)

1(S),9(R)-(-)-Bicuculline methbromide

66016-70-4