ChemicalBook > CAS DataBase List > NU 6027

NU 6027

Product Name
NU 6027
CAS No.
220036-08-8
Chemical Name
NU 6027
Synonyms
NU 6027 USP/EP/BP;NU6027;NU-6027;NU 6027;ATR/CDK Inhibitor, NU6027;6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine;2,6-DiaMino-4-(cyclohexylMethoxy)-5-nitrosopyriMidine;2,4-Pyrimidinediamine, 6-(cyclohexylmethoxy)-5-nitroso-;ATR/CDK Inhibitor, NU6027 - CAS 220036-08-8 - Calbiochem;inhibit,Ataxia telangiectasia mutated,Cyclin dependent kinase,ATM/ATR,NU 6027,cytotoxicity,NU6027,Inhibitor,NU-6027,CDK2,cisplatin,hydroxyurea,ATR,CDK1,CDK,ATM and RAD3 related,cancer
CBNumber
CB3497447
Molecular Formula
C11H17N5O2
Formula Weight
251.29
MOL File
220036-08-8.mol
More
Less

NU 6027 Property

Melting point:
252.5-253.7 °C(lit.)
Boiling point:
549.2±60.0 °C(Predicted)
Density 
1.53±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: 15 mg/mL
pka
2.52±0.10(Predicted)
form 
Reddish-purple powder
color 
lavender
More
Less

Safety

WGK Germany 
3
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
189299
Product name
ATR/CDK Inhibitor, NU6027
Packaging
10mg
Price
$216
Updated
2024/03/01
Cayman Chemical
Product number
16177
Product name
NU 6027
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
16177
Product name
NU 6027
Purity
≥98%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
16177
Product name
NU 6027
Purity
≥98%
Packaging
10mg
Price
$139
Updated
2024/03/01
Cayman Chemical
Product number
16177
Product name
NU 6027
Purity
≥98%
Packaging
50mg
Price
$533
Updated
2024/03/01
More
Less

NU 6027 Chemical Properties,Usage,Production

Uses

NU6027 is a potent cyclin-dependent kinase (CDK) and Rad3-related kinase (ATR) inhibitor. NU6027 has been shown to inhibit tumor cell growth. NU6027 inhibits ATR, impairing G2/M arrest and homologous recombination thus increasing sensitivity to DNA-damaging agents and poly(ADP-ribose) polymerase (PARP) inhibitors

target

CDK1

NU 6027 Preparation Products And Raw materials

Raw materials

Preparation Products

220036-08-8, NU 6027Related Search:


  • ATR/CDK Inhibitor, NU6027 - CAS 220036-08-8 - Calbiochem
  • NU6027;NU-6027;NU 6027
  • 2,4-Pyrimidinediamine, 6-(cyclohexylmethoxy)-5-nitroso-
  • ATR/CDK Inhibitor, NU6027
  • 2,6-DiaMino-4-(cyclohexylMethoxy)-5-nitrosopyriMidine
  • 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine
  • NU 6027 USP/EP/BP
  • inhibit,Ataxia telangiectasia mutated,Cyclin dependent kinase,ATM/ATR,NU 6027,cytotoxicity,NU6027,Inhibitor,NU-6027,CDK2,cisplatin,hydroxyurea,ATR,CDK1,CDK,ATM and RAD3 related,cancer
  • 220036-08-8
  • Inhibitors