ChemicalBook > CAS DataBase List > BETA-ENDORPHIN HUMAN SYNTHETIC
BETA-ENDORPHIN HUMAN SYNTHETIC
- Product Name
- BETA-ENDORPHIN HUMAN SYNTHETIC
- CAS No.
- 61214-51-5
- Chemical Name
- BETA-ENDORPHIN HUMAN SYNTHETIC
- Synonyms
- LPH(61-91);βh-Endorphin;B-ENDORPHIN HUMAN;β-Endorphin human;Β-ENDORPHIN, HUMAN;β- endorphin, people;β-Lipotropin C-fragment;β-Endorphin(1-31)【human】;61-91-β-Lipotropin【human】;?-Endorphin, human - 1 mg
- CBNumber
- CB3497654
- Molecular Formula
- C158H251N39O46S
- Formula Weight
- 3464.99
- MOL File
- 61214-51-5.mol
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BETA-ENDORPHIN HUMAN SYNTHETIC Property
- Boiling point:
- 2931.7±65.0 °C(Predicted)
- Density
- 1.302±0.06 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
- form
- Powder
- color
- White to off-white
- optical activity
- -7420 (0.5 mol dm-3 acetic acid)
- Water Solubility
- Soluble in water.
- Sequence
- Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- E6261
- Product name
- β-Endorphin human
- Purity
- ≥95% (HPLC)
- Packaging
- 250μg
- Price
- $156.91
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- E6261
- Product name
- β-Endorphin human
- Purity
- ≥95% (HPLC)
- Packaging
- 0.5mg
- Price
- $273.21
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- E6261
- Product name
- β-Endorphin human
- Purity
- ≥95% (HPLC)
- Packaging
- 1mg
- Price
- $469.81
- Updated
- 2025/07/31
ChemScene
- Product number
- CS-0031553
- Product name
- β-Endorphin human
- Purity
- 96.63%
- Packaging
- 1mg
- Price
- $140
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0031553
- Product name
- β-Endorphin human
- Purity
- 96.63%
- Packaging
- 5mg
- Price
- $550
- Updated
- 2021/12/16
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BETA-ENDORPHIN HUMAN SYNTHETIC Chemical Properties,Usage,Production
Uses
beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both pre- and post- synaptic nerve terminals, primarily exerting their effect through presynaptic binding. In the central nervous system, beta-endorphins similarly bind mu-opioid receptors and exert their primary action at presynaptic nerve terminals. It is a potent pain suppressant.
General Description
β-Endorphin is a potent endogenous opioid protein that is derived from propiomelanocortin, a protein found in the brain, anterior pituitary, skin, immune system, and other peripheral sites. β-endorphin, however, is localized to the brain and spinal cord. It is one of the major opioid peptides, and is the derivative of the C-terminal of β-lipotropin. It is made of 31 amino acids.
Biochem/physiol Actions
β-Endorphin acts as a ligand for both μ and δ opioid receptors in different parts of the brain. It is released in response to painful stimuli and has potent antinociceptive activity. When given supraspinally, this activity is mediated through its action on ε-opioid receptors in brain that results in the release of Met-enkephalin. This activity is also mediated by its interaction with δ2-opioid receptors in the spinal cord. When introduced intrathecally, this function is an outcome of its interaction with μ and κ-opioid receptors in the rat. In autoimmune disorders, the elevated production of cytokines results in the production of β-endorphin, in pituitary and lymphocytes. This acts as a negative regulator of antibody production, and is thus, implicated in autoimmune diseases.
IC 50
δ Opioid Receptor/DOR
BETA-ENDORPHIN HUMAN SYNTHETIC Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from BETA-ENDORPHIN HUMAN SYNTHETIC manufacturers
Xiamen Wonderful Bio Technology Co., Ltd.
- Product
- β-Endorphin (human) trifluoroacetate salt 61214-51-5
- Price
- US $120.00/KG
- Min. Order
- 1250KG
- Purity
- 99%
- Supply Ability
- 330T
- Release date
- 2023-06-28
61214-51-5, BETA-ENDORPHIN HUMAN SYNTHETICRelated Search:
BETA-ENDORPHIN (RAT)
LYS-LYS-GLY-GLU
H-TYR-GLY-GLY-PHE-OH
BETA-LIPOTROPIN (61-69)
H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Val-His-Lys-Lys-Gly-Gln-OH
β-Interleukin II (44-56)
B-ENDORPHIN (HUMAN) (B-LIPOTROPIN 61-91,
BETA-LIPOTROPIN (1-10) (PORCINE)
BETA-NEOENDORPHIN
β-catenin peptide
H-TYR-PRO-PHE-VAL-GLU-PRO-ILE-OH
GLYCYL-L-GLUTAMIC ACID
H-Tyr-Lys-Lys-Gly-Glu-OH
Glycyl-L-glutamine monohydrate
BETA-ENDORPHIN (CAMEL)
BETA-ENDORPHIN (18-31) (HUMAN)
BETA-ENDORPHIN (EQUINE)
b-Endorphin (6-31), human