ChemicalBook > CAS DataBase List > BETA-ENDORPHIN HUMAN SYNTHETIC

BETA-ENDORPHIN HUMAN SYNTHETIC

Product Name
BETA-ENDORPHIN HUMAN SYNTHETIC
CAS No.
61214-51-5
Chemical Name
BETA-ENDORPHIN HUMAN SYNTHETIC
Synonyms
LPH(61-91);βh-Endorphin;B-ENDORPHIN HUMAN;β-Endorphin human;Β-ENDORPHIN, HUMAN;β- endorphin, people;β-Lipotropin C-fragment;β-Endorphin(1-31)【human】;61-91-β-Lipotropin【human】;Human beta-lipotropin(61-91)
CBNumber
CB3497654
Molecular Formula
C158H251N39O46S
Formula Weight
3464.99
MOL File
61214-51-5.mol
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BETA-ENDORPHIN HUMAN SYNTHETIC Property

Boiling point:
2931.7±65.0 °C(Predicted)
Density 
1.302±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
Powder
color 
White to off-white
optical activity
-7420 (0.5 mol dm-3 acetic acid)
Water Solubility 
Soluble in water.
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
E6261
Product name
β-Endorphin human
Purity
≥95% (HPLC)
Packaging
250μg
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
E6261
Product name
β-Endorphin human
Purity
≥95% (HPLC)
Packaging
1mg
Price
$197.6
Updated
2024/03/01
Sigma-Aldrich
Product number
E6261
Product name
β-Endorphin human
Purity
≥95% (HPLC)
Packaging
0.5mg
Price
$287
Updated
2024/03/01
Alfa Aesar
Product number
J62374
Product name
beta-Endorphin, human
Packaging
1mg
Price
$213
Updated
2023/06/20
ChemScene
Product number
CS-0031553
Product name
β-Endorphin human
Purity
96.63%
Packaging
1mg
Price
$140
Updated
2021/12/16
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BETA-ENDORPHIN HUMAN SYNTHETIC Chemical Properties,Usage,Production

Uses

beta-endorphins produce analgesia by binding to opioid receptors (particularly of the mu subtype) at both pre- and post- synaptic nerve terminals, primarily exerting their effect through presynaptic binding. In the central nervous system, beta-endorphins similarly bind mu-opioid receptors and exert their primary action at presynaptic nerve terminals. It is a potent pain suppressant.

General Description

β-Endorphin is a potent endogenous opioid protein that is derived from propiomelanocortin, a protein found in the brain, anterior pituitary, skin, immune system, and other peripheral sites. β-endorphin, however, is localized to the brain and spinal cord. It is one of the major opioid peptides, and is the derivative of the C-terminal of β-lipotropin. It is made of 31 amino acids.

Biochem/physiol Actions

β-Endorphin acts as a ligand for both μ and δ opioid receptors in different parts of the brain. It is released in response to painful stimuli and has potent antinociceptive activity. When given supraspinally, this activity is mediated through its action on ε-opioid receptors in brain that results in the release of Met-enkephalin. This activity is also mediated by its interaction with δ2-opioid receptors in the spinal cord. When introduced intrathecally, this function is an outcome of its interaction with μ and κ-opioid receptors in the rat. In autoimmune disorders, the elevated production of cytokines results in the production of β-endorphin, in pituitary and lymphocytes. This acts as a negative regulator of antibody production, and is thus, implicated in autoimmune diseases.

BETA-ENDORPHIN HUMAN SYNTHETIC Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BETA-ENDORPHIN HUMAN SYNTHETIC manufacturers

Xiamen Wonderful Bio Technology Co., Ltd.
Product
β-Endorphin (human) trifluoroacetate salt 61214-51-5
Price
US $120.00/KG
Min. Order
1250KG
Purity
99%
Supply Ability
330T
Release date
2023-06-28

61214-51-5, BETA-ENDORPHIN HUMAN SYNTHETICRelated Search:


  • β-Endorphin, human, ≥96% (HPLC)
  • Β-ENDORPHIN, HUMAN
  • BETA-ENDORPHIN HUMAN SYNTHETIC
  • BETA-ENDORPHIN, HUMAN, SYNTETIC
  • B-ENDORPHIN HUMAN
  • β-Lipotropin 61-91, β-Lipotropin C-fragment, LPH (61-91)
  • 61-91-β-Lipotropin【human】
  • β-Endorphin(1-31)【human】
  • βh-Endorphin
  • β-Lipotropin C-fragment
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-PHE-LYS-ASN-ALA-ILE-ILE-LYS-ASN-ALA-TYR: YGGFMTSEKSQTPLVTLFKNAIIKNAY
  • 27-L-Tyrosine-31-L-glutamic acid-beta-endorphin (sheep)
  • beta-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid-
  • LPH(61-91)
  • β-Endorphin (huMan) β-Lipotropin (59-89) (huMan), Lipotropin C FragMent (huMan)
  • b-Lipotropin (59-89) (huMan), Lipotropin C FragMent (huMan)
  • β- endorphin, people
  • Human beta-lipotropin(61-91)
  • L-Tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonyl-L-leucyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-alanyl-L-isoleucyl-L-isoleucyl-L-lysyl-L-asparaginyl-L-alanyl-L-tyrosyl-L-lysyl-L-lysylglycyl-L-glutamic acid
  • β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid-
  • β-Endorphin human
  • β-Endorphin (huMan) β-Lipotropin (59-89) (huMan), Lipotropin C FragMent (huMan)
  • 27-L-Tyrosine-31-L-glutamic acid-beta-endorphin
  • β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid-
  • β-Endorphin TFA salt (human)
  • 61214-51-5
  • C158H251N39O46S