1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&

Product Name: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&
CAS No.: 78269-85-9
Chemical Name: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&
Synonyms: Teoc-OSu;N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide;1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&;1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&(TriMethylsilyl)ethoxycarbonyloxy]succiniMide;1-[[[2-(Trimethylsilyl)ethoxy]carbonyl]oxy]-2;(triMethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-dione;N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide≥ 98%(N);TEOC-OSU N-[2-(trimethylsilyl)ethoxycarbonyloxy]succinimide;N-[2-(trimethylsilyl)ethoxycarbonyloxy]succinimide(Teoc-Osu)
CBNumber: CB3499623
Molecular Formula: C10H17NO5Si
Formula Weight: 259.33
MOL File: 78269-85-9.mol

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1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& Property

Melting point:: 83-88 °C(lit.)
Boiling point:: 308.6±44.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: soluble in Methanol
form: powder to crystal
color: White to Almost white
Hydrolytic Sensitivity: 7: reacts slowly with moisture/water
InChI: InChI=1S/C10H17NO5Si/c1-17(2,3)7-6-15-10(14)16-11-8(12)4-5-9(11)13/h4-7H2,1-3H3
InChIKey: FLDNDAMSCINJDX-UHFFFAOYSA-N
SMILES: C(OCC[Si](C)(C)C)(=O)ON1C(=O)CCC1=O

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2931.90.9010

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 530816
Product name: 1-[2-(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione
Packaging: 1g
Price: $92.45
Updated: 2025/07/31

Sigma-Aldrich

Product number: 530816
Product name: 1-[2-(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione
Packaging: 10g
Price: $285.12
Updated: 2025/07/31

TCI Chemical

Product number: T2591
Product name: N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide
Purity: >98.0%(N)
Packaging: 1g
Price: $42
Updated: 2025/07/31

TCI Chemical

Product number: T2591
Product name: N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide
Purity: >98.0%(N)
Packaging: 5g
Price: $167
Updated: 2025/07/31

TRC

Product number: D487135
Product name: 2,5-Dioxopyrrolidin-1-yl(2-(trimethylsilyl)ethyl)Carbonate
Packaging: 10mg
Price: $45
Updated: 2021/12/16

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1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& Chemical Properties,Usage,Production

Chemical Properties

White to off-white powder

Uses

1-[2-(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione (Teoc-OSu) may be used as an acylating reagent to produce Teoc-amino acid derivatives.

General Description

1-[2-(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione (Teoc-OSu) is a silicon-based reagent that can be prepared from 2-trimethylsilylethyl carbonochloridite and N-hydroxysuccinimide.

Synthesis

6066-82-6

20160-60-5

78269-85-9

2-(Trimethylsilyl)ethyl chloroformate (S13) was dissolved in acetonitrile (105 mL) at 0 °C. Subsequently, N-hydroxybutanediimide (5.22 g, 45.4 mmol, 1.30 eq.) and triethylamine (4.59 g, 45.4 mmol, 1.30 eq.; dissolved in 11.0 mL acetonitrile) were added to the solution. The reaction mixture was kept stirred at 0 °C for 16 hours. After completion of the reaction, the mixture was poured into water. The aqueous layer was extracted with ether (6 times). The organic layers were combined and washed sequentially with water (2 times), 1.0 M hydrochloric acid and then with water, followed by drying with magnesium sulfate. The dried organic phase was filtered and concentrated under reduced pressure to give 1-[2-(trimethylmethylsilyl)ethoxycarbonyloxy]pyrrolidine-2,5-dione (S14, 7.72 g, 29.8 mmol, 85% yield in two steps) as a colorless solid.

References

[1] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 564 - 570
[2] Synthesis, 1987, # 4, p. 346 - 349
[3] Patent: US6627660, 2003, B1
[4] Patent: US2004/116391, 2004, A1

1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& Suppliers

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View Lastest Price from 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& 78269-85-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& 78269-85-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)& 78269-85-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

78269-85-9, 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&Related Search:

1-[(2-TRIMETHYLSILYL)ETHOXYCARBONYLOXY]PYRROLIDIN-2,5-DIONE 1-[2-(Trimethylsilyl)ethoxycarbonyloxy]benzotriazole 2-(Trimethylsilyl)ethanol 1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&

1-({[2-(trimethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-dione

N-[2-(trimethylsilyl)ethoxycarbonyloxy]succinimide(Teoc-Osu)

1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&

N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide

Teoc-OSu

(TriMethylsilyl)ethoxycarbonyloxy]succiniMide

2,5-Dioxopyrrolidin-1-yl (2-(trimethylsilyl)-ethyl) carbonate

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(triMethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-dione

Carbonic acid 2,5-dioxo-pyrrolidin-1-yl [2-(trimethylsilyl)ethyl] ester

N-[2-(Trimethylsilyl)ethoxycarbonyloxy]succinimide≥ 98%(N)

1-[[[2-(Trimethylsilyl)ethoxy]carbonyl]oxy]-2

TEOC-OSU N-[2-(trimethylsilyl)ethoxycarbonyloxy]succinimide

1-({[2-(trimethylsilyl)ethoxy]carbonyl}oxy)pyrrolidine-2,5-d...

2,5-Dioxo-1-pyrrolidinyl [2-(trimethylsilyl)ethyl] carbonate

1-(2-(TRIMETHYLSILYL)ETHOXYCARBONYLOXY)&amp

1-[2-(Trimethylsilyl)ethoxycarbonyloxy]pyrrolidin-2,5-dione

78269-85-9

C10H17NO5Si

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Heterocyclic Building Blocks

Pyrrolidines