(R)-(+)-AMINOGLUTETHIMIDE 97
- Product Name
- (R)-(+)-AMINOGLUTETHIMIDE 97
- CAS No.
- 55511-44-9
- Chemical Name
- (R)-(+)-AMINOGLUTETHIMIDE 97
- Synonyms
- CGS-2396;Aminoglutethimide, D-;(R)-(+)-AMINOGLUTETHIMIDE 97;(R)-(+)-Aminoglutethimide 97%;(R)-(+)-Aminoglutethimide;(R)-3-(4-Aminophenyl)-3-ethyl-2,6-piperidinedione;(R)-3-(4-aMinophenyl)-3-ethylpiperidine-2,6-dione;(3R)-3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione;2,6-Piperidinedione, 3-(4-aminophenyl)-3-ethyl-, (3R)-
- CBNumber
- CB3499719
- Molecular Formula
- C13H16N2O2
- Formula Weight
- 232.28
- MOL File
- 55511-44-9.mol
(R)-(+)-AMINOGLUTETHIMIDE 97 Property
- Melting point:
- 115.5-119.5 °C (lit.)
- Boiling point:
- 457.4±45.0 °C(Predicted)
- Density
- 1.173±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Solid
- pka
- 11.60±0.40(Predicted)
- color
- Off-white to light yellow
- optical activity
- [α]20/D +160°, c = 1 in methanol
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 545872
- Product name
- (R)-(+)-Aminoglutethimide
- Purity
- 97%
- Packaging
- 500mg
- Price
- $196.88
- Updated
- 2025/07/31
- Product number
- API0009817
- Product name
- (R)-(+)-AMINOGLUTETHIMIDE
- Purity
- 97.00%
- Packaging
- 5MG
- Price
- $499.72
- Updated
- 2021/12/16
(R)-(+)-AMINOGLUTETHIMIDE 97 Chemical Properties,Usage,Production
Uses
(R)-(+)-Aminoglutethimide can be used:
- As a building block for the development of cephalosporin based prodrug for antibody-directed enzyme prodrug therapy (ADEPT).
- To prepare (R)-3-ethyl-3-(4-(3,4,5-trimethoxybenzylamino)phenyl)piperidine-2,6-dione by reacting with 3,4,5-trimethoxybenzylamine via deaminative coupling reaction.
- To synthesize (R)-2-fluoro-2-(4-methoxyphenyl)-N-(R)-(+)-aminoglutethimide by enantioselective α-fluorination.
Definition
ChEBI: The (3R)-enantiomer of aminoglutethimide.
in vivo
(R)-(+)-Aminoglutethimide (5, 50 mg/kg; p.o.) eliminates within 48 hr into urine and feces, mostly in the form of metabolites[2].
(R)-(+)-Aminoglutethimide (1, 10, 50 mg/kg; i.p.; 60 min before training) dose not induce any significant effect in 1 and 10 mg/kg, induces a loss of retention at 50 mg/kg in day-old chicks[3].
IC 50
Aromatase
(R)-(+)-AMINOGLUTETHIMIDE 97 Preparation Products And Raw materials
Raw materials
Preparation Products
(R)-(+)-AMINOGLUTETHIMIDE 97 Suppliers
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- Country
- Switzerland
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