MLS0315771

Product Name: MLS0315771
CAS No.: 727664-91-7
Chemical Name: MLS0315771
Synonyms: MLS0315771;MLS0315771, 10 mM in DMSO;MLS0315771,MLS-0315771,Inhibitor,MLS 0315771,inhibit;2-(2,5-Dimethylphenyl)-6-fluorobenzo[d]isothiazol-3(2H)-one;1,2-Benzisothiazol-3(2H)-one, 2-(2,5-dimethylphenyl)-6-fluoro-;2-(2,5-dimethylphenyl)-6-fluoro-2,3-dihydro-1,2-benzothiazol-3-one;2-(2,5-dimethylphenyl)-6-fluoro-2,3-dihydro-1,2-benzothiazole-3-one
CBNumber: CB35419790
Molecular Formula: C15H12FNOS
Formula Weight: 273.33
MOL File: 727664-91-7.mol

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MLS0315771 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: Light yellow to brown

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Hazard and Precautionary Statements (GHS)

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MLS0315771 Chemical Properties,Usage,Production

Uses

MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM.

Definition

ChEBI: 2-(2,5-dimethylphenyl)-6-fluoro-1,2-benzothiazol-3-one is a member of benzothiazoles.

References

[1] Sharma V, et al. Phosphomannose isomerase inhibitors improve N-glycosylation in selected phosphomannomutase-deficient fibroblasts. J Biol Chem. 2011 Nov 11;286(45):39431-8. DOI:10.1074/jbc.M111.285502

MLS0315771 Preparation Products And Raw materials

Raw materials

Preparation Products

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MLS0315771 Suppliers

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727664-91-7, MLS0315771Related Search:

MLS0315771

1,2-Benzisothiazol-3(2H)-one, 2-(2,5-dimethylphenyl)-6-fluoro-

2-(2,5-dimethylphenyl)-6-fluoro-2,3-dihydro-1,2-benzothiazol-3-one

2-(2,5-dimethylphenyl)-6-fluoro-2,3-dihydro-1,2-benzothiazole-3-one

MLS0315771,MLS-0315771,Inhibitor,MLS 0315771,inhibit

MLS0315771, 10 mM in DMSO

2-(2,5-Dimethylphenyl)-6-fluorobenzo[d]isothiazol-3(2H)-one

727664-91-7