ChemicalBook > CAS DataBase List > 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate

1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate

Product Name
1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
CAS No.
2158302-00-0
Chemical Name
1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
Synonyms
(S)-2-(4-Boc-1-Cbz-2-piperazinyl)acetonitrile;O1-benzyl O4-tert-butyl (2S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate;2-Cyanomethyl-piperazine-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester;1,4-Piperazinedicarboxylic acid, 2-(cyanomethyl)-, 4-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2S)-
CBNumber
CB35441874
Molecular Formula
C19H25N3O4
Formula Weight
359.42
MOL File
2158302-00-0.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0089649
Product name
1-Benzyl4-(tert-butyl)(S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
Purity
96.32%
Packaging
100mg
Price
$118
Updated
2021/12/16
ChemScene
Product number
CS-0089649
Product name
1-Benzyl4-(tert-butyl)(S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
Purity
96.32%
Packaging
250mg
Price
$200
Updated
2021/12/16
ChemScene
Product number
CS-0089649
Product name
1-Benzyl4-(tert-butyl)(S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
Purity
96.32%
Packaging
1g
Price
$470
Updated
2021/12/16
ChemScene
Product number
CS-0089649
Product name
1-Benzyl4-(tert-butyl)(S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
Purity
96.32%
Packaging
5g
Price
$1482
Updated
2021/12/16
Chemenu
Product number
CM335971
Product name
1-Benzyl4-(tert-butyl)(S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
Purity
95%+
Packaging
5g
Price
$2342
Updated
2021/12/16
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1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

Dissolve (S)-3-(cyanomethyl)piperazine-1-carboxylic acid tert-butyl ester (2.25g, 10mmol) in 15mL dichloromethane, add N,N-diisopropylethylamine at room temperature (3.87g, 30mmol) was cooled to 0°C, benzyl chloroformate was added dropwise, and reacted at low temperature for 2h. Add 25 mL of water to the reaction solution, extract the aqueous phase with dichloromethane (30 mL×3), combine the organic phases, wash the organic phase with water (20 mL×2), dry with anhydrous sodium sulfate, concentrate, and separate and purify the crude product by silica gel column chromatography (Ethyl acetate/petroleum ether (v/v)=1:20-1:5) to obtain 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate (3.1 g, yield: 86%).

1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate Suppliers

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2158302-00-0, 1-Benzyl 4-(tert-butyl) (S)-2-(cyanomethyl)piperazine-1,4-dicarboxylateRelated Search:


  • 1,4-Piperazinedicarboxylic acid, 2-(cyanomethyl)-, 4-(1,1-dimethylethyl) 1-(phenylmethyl) ester, (2S)-
  • 2-Cyanomethyl-piperazine-1,4-dicarboxylic acid 1-benzyl ester 4-tert-butyl ester
  • (S)-2-(4-Boc-1-Cbz-2-piperazinyl)acetonitrile
  • O1-benzyl O4-tert-butyl (2S)-2-(cyanomethyl)piperazine-1,4-dicarboxylate
  • 2158302-00-0