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ATP synthase inhibitor 1

Product Name
ATP synthase inhibitor 1
CAS No.
1023043-30-2
Chemical Name
ATP synthase inhibitor 1
Synonyms
ATP SYNTHASE INHIBITOR 1;1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(5-chloro-2-thienyl)sulfonyl]-1-phenyl-;8-((5-Chlorothiophen-2-yl)sulfonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;ATP Synthase,ATP synthase inhibitor 1,Inhibitor,inhibit,ATP synthase inhibitor-1,ATP synthase inhibitor1
CBNumber
CB35540366
Molecular Formula
C17H18ClN3O3S2
Formula Weight
411.93
MOL File
1023043-30-2.mol
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ATP synthase inhibitor 1 Property

Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C,unstable in solution, ready to use.
solubility 
DMSO: 5 mg/mL (12.14 mM)
pka
14.80±0.20(Predicted)
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0062826
Product name
ATPsynthaseinhibitor1
Purity
99.84%
Packaging
5mg
Price
$300
Updated
2021/12/16
ChemScene
Product number
CS-0062826
Product name
ATPsynthaseinhibitor1
Purity
99.84%
Packaging
10mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0062826
Product name
ATPsynthaseinhibitor1
Purity
99.84%
Packaging
50mg
Price
$1200
Updated
2021/12/16
ChemScene
Product number
CS-0062826
Product name
ATPsynthaseinhibitor1
Purity
99.84%
Packaging
100mg
Price
$1800
Updated
2021/12/16
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ATP synthase inhibitor 1 Chemical Properties,Usage,Production

Description

ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1]. F1/FO-ATP synthase[1]

ATP synthase inhibitor 1 (Compound 10) is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex[1].

Uses

ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels[1].

References

[1]. Morciano G, et al. Discovery of Novel 1,3,8-Triazaspiro[4.5]decane Derivatives That Target the c Subunit of F1/FO-Adenosine Triphosphate (ATP) Synthase for the Treatment of Reperfusion Damage in Myocardial Infarction. J Med Chem. 2018 Aug 23;61(16):7131-7143.

ATP synthase inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

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ATP synthase inhibitor 1 Suppliers

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1023043-30-2, ATP synthase inhibitor 1Related Search:


  • ATP SYNTHASE INHIBITOR 1
  • ATP Synthase,ATP synthase inhibitor 1,Inhibitor,inhibit,ATP synthase inhibitor-1,ATP synthase inhibitor1
  • 1,3,8-Triazaspiro[4.5]decan-4-one, 8-[(5-chloro-2-thienyl)sulfonyl]-1-phenyl-
  • 8-((5-Chlorothiophen-2-yl)sulfonyl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
  • 1023043-30-2