ML401

Product Name: ML401
CAS No.: 1597489-14-9
Chemical Name: ML401
Synonyms: ML401;CID73169083;ML401 ，E0106;ML401 (CID73169083);ML401, 10 mM in DMSO;ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401;(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one;(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one;2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-
CBNumber: CB35559120
Molecular Formula: C20H20BrClN2O
Formula Weight: 419.74
MOL File: 1597489-14-9.mol

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ML401 Property

Boiling point:: 557.2±50.0 °C(Predicted)
Density: 1.422±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO: 10.42 mg/mL (24.82 mM)
pka: 5.99±0.10(Predicted)
form: Solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 5mg
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 10mg
Price: $550
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 25mg
Price: $990
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 50mg
Price: $1650
Updated: 2021/12/16

ChemScene

Product number: CS-0066585
Product name: ML401
Purity: 99.87%
Packaging: 100mg
Price: $2250
Updated: 2021/12/16

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ML401 Chemical Properties,Usage,Production

Uses

ML401, a potent chemical probe, selectively antagonizes EBI2 (also known as GPR183) with an IC50 of 1.03 nM. ML401 displays activity in a chemotaxis assay (IC50=6.24 nM). ML401 shows good stability and no toxicity[1].

in vivo

ML401 shows very good stability in both human plasma and mouse plasma^[1].

References

[1] Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet]. PMID:25834900

ML401 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML401 Suppliers

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1597489-14-9, ML401Related Search:

ML401

CID73169083

2-Propen-1-one, 3-(4-bromophenyl)-1-[4-[(4-chlorophenyl)methyl]-1-piperazinyl]-, (2E)-

(E)-3-(4-Bromophenyl)-1-(4-(4-chlorobenzyl)piperazin-1-yl)prop-2-en-1-one

ML401 (CID73169083)

ML401,Inhibitor,ML 401,EBI2/GPR183,inhibit,ML-401

(E)-3-(4-Bromophenyl)-1-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one

ML401, 10 mM in DMSO

ML401 ，E0106

1597489-14-9

C20H20BrClN2O