GNE-8324

Product Name: GNE-8324
CAS No.: 1698901-76-6
Chemical Name: GNE-8324
Synonyms: GNE8324;GNE 8324;GNE-8324;GNE-8324; GNE 8324; GNE8324;4H,6H-Cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one, 2-[[ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-;10-{[ethyl(4-fluorophenyl)amino]methyl}-7-thia-1,9-diazatricyclo[6.4.0.02,?]dodeca-2(6),8,10-trien-12-one
CBNumber: CB35582377
Molecular Formula: C18H18FN3OS
Formula Weight: 343.42
MOL File: 1698901-76-6.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd

Product number: orb611954
Product name: GNE-8324
Purity: >98%
Packaging: 10mg
Price: $912.9
Updated: 2021/12/16

ChemScene

Product number: CS-0028635
Product name: GNE-8324
Packaging: 25mg
Price: $950
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611954
Product name: GNE-8324
Purity: >98%
Packaging: 25mg
Price: $1654.1
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611954
Product name: GNE-8324
Purity: >98%
Packaging: 100mg
Price: $2839
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611955
Product name: GNE-8324
Purity: >98%
Packaging: 10mg
Price: $3282.7
Updated: 2021/12/16

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GNE-8324 Chemical Properties,Usage,Production

Description

GNE-8324 is a potent and selective NMDA receptor PAM.

in vitro

This study showed previously that NMDAR positive allosteric modulator GNE-8324 and M-8324 selectively increase NMDAR activity on the inhibitory neurons and elevates their activity in vitro and in vivo._x000D_ _x000D_ Reference: Front Pharmacol. 2022 Jan 4;12:796179. https://pubmed.ncbi.nlm.nih.gov/35058780/

target

GNE-8324 is a selective GluN2A positive allosteric modulator. GNE-8324 selectively enhances NMDA receptor (NMDAR)-mediated synaptic responses in inhibitory but not excitatory neurons.

GNE-8324 Preparation Products And Raw materials

Raw materials

Preparation Products

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GNE-8324 Suppliers

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1698901-76-6, GNE-8324Related Search:

GNE 8324

GNE8324

GNE-8324

GNE-8324; GNE 8324; GNE8324

4H,6H-Cyclopenta[4,5]thiazolo[3,2-a]pyrimidin-4-one, 2-[[ethyl(4-fluorophenyl)amino]methyl]-7,8-dihydro-

10-{[ethyl(4-fluorophenyl)amino]methyl}-7-thia-1,9-diazatricyclo[6.4.0.02,?]dodeca-2(6),8,10-trien-12-one

1698901-76-6