Abemaciclib Metabolites M2

Product Name: Abemaciclib Metabolites M2
CAS No.: 1231930-57-6
Chemical Name: Abemaciclib Metabolites M2
Synonyms: LSN2839567;Des-Et-Abemaciclib;Abemaciclib Impurity 41;Abemaciclib Impurity 44;Abemaciclib Impurity 11;Abemaciclib Impurity 43;Abemaciclib Impurity 42;Abemaciclib M2 Metabolite;Abemaciclib metabolite M2;Abemaciclib Metabolites M2
CBNumber: CB35821258
Molecular Formula: C25H28F2N8
Formula Weight: 478.54
MOL File: 1231930-57-6.mol

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Abemaciclib Metabolites M2 Property

Boiling point:: 690.9±65.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9.01±0.10(Predicted)
form: Solid
color: Light yellow to yellow
InChIKey: IXGZDCRFGCEEBU-UHFFFAOYSA-N
SMILES: C1(NC2=NC=C(CN3CCNCC3)C=C2)=NC=C(F)C(C2C=C3N(C(C)C)C(C)=NC3=C(F)C=2)=N1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0096557
Product name: AbemaciclibmetaboliteM2
Purity: 99.82%
Packaging: 1mg
Price: $320
Updated: 2021/12/16

ChemScene

Product number: CS-0096557
Product name: AbemaciclibmetaboliteM2
Purity: 99.82%
Packaging: 5mg
Price: $960
Updated: 2021/12/16

ChemScene

Product number: CS-0096557
Product name: AbemaciclibmetaboliteM2
Purity: 99.82%
Packaging: 10mg
Price: $1600
Updated: 2021/12/16

AK Scientific

Product number: 4210DP
Product name: AbemaciclibMetabolitesM2
Packaging: 1g
Price: $2692
Updated: 2021/12/16

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Abemaciclib Metabolites M2 Chemical Properties,Usage,Production

Uses

Des-Et-Abemaciclib is an impurity of Abemaciclib (A115153) is a potent and selective inhibitor of cyclin-dependent kinases, CDK4 and CDK6, as a method to inhibit the proliferation of cancer cells.

in vivo

Abemaciclib metabolite M2 (LSN2839567) is bound to plasma proteins in rat, dog and human (83-92%), lower than Abemaciclib (95-99%)^[2].
Abemaciclib metabolite M2 is the most prominent (active and major) plasma metabolites in human^[2].

IC 50

CDK4: 1.2 nM (IC₅₀); CDK6: 1.3 nM (IC₅₀)

Abemaciclib Metabolites M2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Abemaciclib Metabolites M2 Suppliers

China 44 India 2 United States 4 Global 50

Nanjing XiZe Biotechnology CO., Ltd.

Tel: 025-66023220 15250997978
Fax: 025-58362220
Email: 1511893459@qq.com
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ProdList: 4876
Advantage: 55

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: marketing@accelachem.com
Country: China
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BOC Sciences

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Bide Pharmatech Ltd.

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Fax: +86-21-61629029
Email: product02@bidepharm.com
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Shandong Zhonghan Pharmaceutical Co.,Ltd.

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ShangHai Biochempartner Co.,Ltd

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Hubei Yangxin Medical Technology Co., Ltd.

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Email: 3003392093@yongstandards.com
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Fan De(Beijing) Biotechnology Co., Ltd.

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Email: liming@bio-fount.com
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
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Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 21193
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View Lastest Price from Abemaciclib Metabolites M2 manufacturers

Moxin Chemicals

Product: Abemaciclib Nitroso Impurity 43 1231930-57-6
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 99%+ HPLC
Supply Ability: 1000
Release date: 2025-07-18

Moxin Chemicals

Product: Abemaciclib Impurity 43 1231930-57-6
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 95%+
Supply Ability: 10000
Release date: 2025-03-05

1231930-57-6, Abemaciclib Metabolites M2Related Search:

Abemaciclib Metabolites M2

5-Fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)-N-[5-(1-piperazinylmethyl)-2-pyridyl]pyrimidin-2-amine

Abemaciclib metabolite M2

2-Pyrimidinamine, 5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-N-[5-(1-piperazinylmethyl)-2-pyridinyl]-

Abemaciclib M2 Metabolite

LSN2839567

1-ethyl-4-((6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methyl)piperazine 1-oxide

Des-Et-Abemaciclib

Abemaciclib Impurity 11

Abemaciclib Impurity 44

Abemaciclib Impurity 41

Abemaciclib Impurity 43

Abemaciclib Nitroso Impurity 43

Abemaciclib Impurity 42

1231930-57-6

C25H28F2N8