Dacomitinib Impurity WYH

Product Name: Dacomitinib Impurity WYH
CAS No.: 2190490-31-2
Chemical Name: Dacomitinib Impurity WYH
Synonyms: Dacotinib impurity 2;Dacomitinib Impurity 3;Dacomitinib Impurity WYH;Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one;2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-;1-(4-((3-Chloro-4-fluorocyclohexyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one;1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)
CBNumber: CB35822563
Molecular Formula: C19H16ClFN4O3
Formula Weight: 402.81
MOL File: 2190490-31-2.mol

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Dacomitinib Impurity WYH Property

Boiling point:: 662.5±55.0 °C(Predicted)
Density: 1.524±0.06 g/cm3(Predicted)
pka: 12.39±0.20(Predicted)

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Hazard and Precautionary Statements (GHS)

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Dacomitinib Impurity WYH Chemical Properties,Usage,Production

Uses

Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one is a derivative of Dacomitinib (D101575), which is an Erb-inhibitor, or an inhibitor of the members of the epidermal growth factor receptor family. Used as an ant-cancer agent due to observation of over-expressed epidermal growth factor receptor in nearly all cases of squamous cell carcinoma in the head and neck.

Dacomitinib Impurity WYH Preparation Products And Raw materials

Raw materials

Preparation Products

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2190490-31-2, Dacomitinib Impurity WYHRelated Search:

Dacomitinib Impurity WYH

Dacomitinib Impurity 3

2-Pyrrolidinone, 1-[4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-5-hydroxy-

Des-(4-(1-piperidinyl)-2-Butenamide) Dacomitinib-5-hydroxypyrrolidin-2-one

1-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one (Dacomitinib Impurity)

1-(4-((3-Chloro-4-fluorocyclohexyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one

Dacotinib impurity 2

2190490-31-2