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(-)-Donepezil

Product Name
(-)-Donepezil
CAS No.
142057-80-5
Chemical Name
(-)-Donepezil
Synonyms
S-(-)-DONEPEZIL;1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, (2S)-
CBNumber
CB35985945
Molecular Formula
C24H29NO3
Formula Weight
379.49
MOL File
142057-80-5.mol
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(-)-Donepezil Property

Melting point:
108-110°C
Boiling point:
527.9±50.0 °C(Predicted)
Density 
1.141±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
pka
8.84±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D531765
Product name
(-)-Donepezil
Packaging
1mg
Price
$185
Updated
2021/12/16
TRC
Product number
D531765
Product name
(-)-Donepezil
Packaging
10mg
Price
$1455
Updated
2021/12/16
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(-)-Donepezil Chemical Properties,Usage,Production

Uses

(-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.

Definition

ChEBI: Donepezil is a racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a nootropic agent and an EC 3.1.1.8 (cholinesterase) inhibitor. It contains a (R)-donepezil and a (S)-donepezil. It is a conjugate base of a donepezil (1+).

(-)-Donepezil Preparation Products And Raw materials

Raw materials

Preparation Products

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(-)-Donepezil Suppliers

Beijing Biocreative Technology Co., Ltd.
Tel
15522676233
Email
3007606172@qq.com
Country
China
ProdList
1248
Advantage
58
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
19704
Advantage
58
TargetMol Chemicals Inc.
Tel
+8613564774135
Email
zijue.cai@tsbiochem.com
Country
United States
ProdList
19885
Advantage
58

142057-80-5, (-)-DonepezilRelated Search:


  • 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, (2S)-
  • S-(-)-DONEPEZIL
  • 142057-80-5