ChemicalBook > CAS DataBase List > (-)-Donepezil
(-)-Donepezil
- Product Name
- (-)-Donepezil
- CAS No.
- 142057-80-5
- Chemical Name
- (-)-Donepezil
- Synonyms
- S-(-)-DONEPEZIL;1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, (2S)-
- CBNumber
- CB35985945
- Molecular Formula
- C24H29NO3
- Formula Weight
- 379.49
- MOL File
- 142057-80-5.mol
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(-)-Donepezil Property
- Melting point:
- 108-110°C
- Boiling point:
- 527.9±50.0 °C(Predicted)
- Density
- 1.141±0.06 g/cm3(Predicted)
- storage temp.
- -20°C Freezer
- solubility
- Acetone (Slightly), Chloroform (Slightly), Methanol (Slightly)
- pka
- 8.84±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
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N-Bromosuccinimide Price
TRC
- Product number
- D531765
- Product name
- (-)-Donepezil
- Packaging
- 1mg
- Price
- $185
- Updated
- 2021/12/16
TRC
- Product number
- D531765
- Product name
- (-)-Donepezil
- Packaging
- 10mg
- Price
- $1455
- Updated
- 2021/12/16
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(-)-Donepezil Chemical Properties,Usage,Production
Uses
(-)-Donepezil is an isomer of Donepezil (D531750), a nootropic, acting as an inhibitor of acetylcholinesterase.
Definition
ChEBI: Donepezil is a racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, a nootropic agent and an EC 3.1.1.8 (cholinesterase) inhibitor. It contains a (R)-donepezil and a (S)-donepezil. It is a conjugate base of a donepezil (1+).
(-)-Donepezil Preparation Products And Raw materials
Raw materials
Preparation Products
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(-)-Donepezil Suppliers
- Tel
- +8613564774135
- zijue.cai@tsbiochem.com
- Country
- United States
- ProdList
- 19863
- Advantage
- 58