ChemicalBook > CAS DataBase List > MAGAININ II

MAGAININ II

Product Name
MAGAININ II
CAS No.
108433-95-0
Chemical Name
MAGAININ II
Synonyms
MAGAININ 2;Aids007842;MAGAININ II;Aids-007842;Magainin II peptide;MAGAININ II USP/EP/BP;GIGKFLHSAKKFGKAFVGEIMNS;Magainin II, ≥97% (HPLC);Magainin 2 (Xenopus laevis);Magainin 2 peptide, Xenopus
CBNumber
CB3664319
Molecular Formula
C114H180N30O29S
Formula Weight
2466.9
MOL File
108433-95-0.mol
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MAGAININ II Property

Boiling point:
2444.0±65.0 °C(Predicted)
Density 
1.275±0.06 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
Sequence
H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M7402
Product name
Magainin II
Purity
≥97% (HPLC)
Packaging
0.1mg
Price
$142.2
Updated
2024/03/01
Sigma-Aldrich
Product number
M7402
Product name
Magainin II
Purity
≥97% (HPLC)
Packaging
0.5mg
Price
$484.2
Updated
2024/03/01
Alfa Aesar
Product number
J61172
Product name
Magainin II
Packaging
0.5mg
Price
$73.4
Updated
2021/12/16
Alfa Aesar
Product number
J61172
Product name
Magainin II
Packaging
1mg
Price
$126
Updated
2021/12/16
Sigma-Aldrich
Product number
M7402
Product name
Magainin II
Purity
≥97% (HPLC)
Packaging
1mg
Price
$1460
Updated
2023/06/20
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MAGAININ II Chemical Properties,Usage,Production

General Description

Magainin II is a member of the antimicrobial peptides family. It is a cationic peptide with Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser amino acid sequence. Magainin II is water soluble and non-hemolytic at its effective and amphiphilic antimicrobial concentrations.

Biochem/physiol Actions

Magainin II acts as an antibiotic in a variety of organisms. Magainin II exhibits cytotoxic and anti-proliferative effects via pore formation in bladder cancer cells. In mice, it acts as an anti-tumor agent in several cancer cell lines and tumors. Magainin II facilitates lactate dehydrogenase discharge from mammalian cells. It directly interacts with certain cell membranes via amphiphilic α-helix and forms permeable ion channels, which results in depolarization and irreversible cytolysis and finally cell death. At low concentrations, Magainin II retards the growth of bacterial and fungal species and it promotes cytolysis in protozoa.

storage

-20°C

MAGAININ II Preparation Products And Raw materials

Raw materials

Preparation Products

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MAGAININ II Suppliers

Zhejiang Jiekun Biotechnology Co., Ltd
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View Lastest Price from MAGAININ II manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Magainin II 108433-95-0
Price
US $0.10-0.30/kg
Min. Order
1kg
Purity
>98%
Supply Ability
20 tons
Release date
2024-01-16
Henan Bao Enluo International TradeCo.,LTD
Product
Magainin I,10-L-lysine-22-L-asparagine 108433-95-0
Price
US $45.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2023-05-18
Career Henan Chemical Co
Product
MAGAININ II 108433-95-0
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-11

108433-95-0, MAGAININ IIRelated Search:


  • H-GLY-ILE-GLY-LYS-PHE-LEU-HIS-SER-ALA-LYS-LYS-PHE-GLY-LYS-ALA-PHE-VAL-GLY-GLU-ILE-MET-ASN-SER-OH
  • GLY-ILE-GLY-LYS-PHE-LEU-HIS-SER-ALA-LYS-LYS-PHE-GLY-LYS-ALA-PHE-VAL-GLY-GLU-ILE-MET-ASN-SER
  • GIGKFLHSAKKFGKAFVGEIMNS
  • MAGAININ II
  • MAGAININ 2
  • 96: PN: WO2009015163 SEQID: 98 unclaimed protein
  • Magainin 2 (Xenopus laevis)
  • Magainin II peptide
  • WO2011023702 SEQID: 10 claimed protein
  • Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH
  • Gly-L-Ile-Gly-L-Lys-L-Phe-L-Leu-L-His-L-Ser-L-Ala-L-Lys-L-Lys-L-Phe-Gly-L-Lys-L-Ala-L-Phe-L-Val-Gly-L-Glu-L-Ile-L-Met-L-Asn-L-Ser-OH
  • Aids007842
  • Aids-007842
  • Magainin II, ≥97% (HPLC)
  • Magainin 2 peptide, Xenopus
  • Magainin I, 10-L-lysine-22-L-asparagine-
  • MAGAININ II USP/EP/BP
  • 108433-95-0
  • C114H180N30O29S
  • C114H180N30O29S1
  • Cell Biology
  • BioChemical
  • Cell Signaling and Neuroscience
  • Immune Cell Signaling and Blood
  • Immune System Regulation
  • Immunomodulators and Antibiotics
  • Peptide
  • Immunomodulators and AntibioticsAntibiotics
  • Antibiotic PeptidesImmune Cell Signaling and Blood
  • Chemical Structure Class
  • Immune System Regulation
  • Immunomodulators
  • Interferes with Cell Membrane Permeability (Ionophores)Antibiotics
  • Mechanism of Action
  • Peptides
  • Peptides for Cell Biology