5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE

Product Name: 5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
CAS No.: 103646-82-8
Chemical Name: 5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE
Synonyms: BUTTPARK 51\09-61;5-Amino-1-(p-tolyl)pyrazole-4-carbonitrile;5-AMINO-4-CYANO-1-(4-METHYLPHENYL)PYRAZOLE;5-AMINO-1-P-TOLYL-1H-PYRAZOLE-4-CARBONITRILE;5-amino-1-toluene-1h-pyrazole-4-methylnitrile;5-Amino-1-(4-methylphenyl)pyrazole-4-carbonitrile;5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE;1H-Pyrazole-4-carbonitrile, 5-amino-1-(4-methylphenyl)-;4-(5-Amino-4-cyano-1H-pyrazol-1-yl)toluene, 5-Amino-4-cyano-1-(4-methylphenyl)-1H-pyrazole
CBNumber: CB3673067
Molecular Formula: C11H10N4
Formula Weight: 198.22
MOL File: 103646-82-8.mol

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5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Property

Melting point:: 116-120
Boiling point:: 405.6±40.0 °C(Predicted)
Density: 1.23±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: powder to crystal
pka: -0.58±0.10(Predicted)
color: White to Orange to Green
CAS DataBase Reference: 103646-82-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933199090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: A3039
Product name: 5-Amino-1-(p-tolyl)pyrazole-4-carbonitrile
Packaging: 1G
Price: $136
Updated: 2025/07/31

TRC

Product number: A576690
Product name: 5-Amino-1-(4-Methylphenyl)-1H-pyrazole-4-carbonitrile
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: A576690
Product name: 5-Amino-1-(4-Methylphenyl)-1H-pyrazole-4-carbonitrile
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: A576690
Product name: 5-Amino-1-(4-Methylphenyl)-1H-pyrazole-4-carbonitrile
Packaging: 500mg
Price: $110
Updated: 2021/12/16

Matrix Scientific

Product number: 043150
Product name: 5-Amino-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile
Purity: >95%
Packaging: 500mg
Price: $118
Updated: 2021/12/16

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5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Chemical Properties,Usage,Production

Synthesis

123-06-8

539-44-6

103646-82-8

GENERAL METHOD: p-Methylphenylhydrazine (0.001 mol) was mixed with 10 mL of ethanol, stirred and heated to reflux. Subsequently, ethoxymethylene malononitrile (0.001 mol) dissolved in 10 mL of ethanol was added slowly and dropwise. The reaction mixture was kept at reflux for 2 hours. After completion of the reaction, the mixture was poured into 50 mL of ice water. The precipitated solid product was collected by filtration and washed with cold water to give the final 5-amino-1-toluene-1H-pyrazole-4-carbonitrile in 61-80% yield.

References

[1] Medicinal Chemistry Research, 2018, vol. 27, # 8, p. 1876 - 1884
[2] Heterocyclic Communications, 2005, vol. 11, # 5, p. 385 - 388
[3] European Journal of Medicinal Chemistry, 2008, vol. 43, # 4, p. 771 - 780
[4] Journal of Organic Chemistry, 1956, vol. 21, p. 1240,1242
[5] Bioorganic and Medicinal Chemistry Letters, 2004, vol. 14, # 9, p. 2121 - 2125

5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE Suppliers

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103646-82-8, 5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILERelated Search:

5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-amino-1-[2-nitro-4-(trifluoromethyl)phenyl]-1H-pyrazole-4-carbonitrile AKOS BBS-00002124 4-(5-amino-4-cyano-1H-pyrazol-1-yl)benzoic acid 5-amino-1-(2-methylphenyl)-1H-pyrazole-4-carbonitrile 5-AMINO-1-(3-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE 5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-3-CARBONITRILE 5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-& 5-amino-3-(2,4-dichlorophenyl)-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile 5-amino-3-(2-chloro-4-methylphenyl)-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile 5-amino-3-(3-fluorophenyl)-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile 5-AMINO-3-METHYL-1-[4-(TRIFLUOROMETHYL)PHENYL]-1H-PYRAZOLE-4-CARBONITRILE BUTTPARK 34\09-22 N'-[4-CYANO-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N,N-DIMETHYLIMINOFORMAMIDE 5-amino-3-(2-fluorophenyl)-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile AKOS BBS-00002122 N-[4-CYANO-1-(4-METHYLPHENYL)-1H-PYRAZOL-5-YL]-N'-HYDROXYIMINOFORMAMIDE 5-amino-3-[3-(trifluoromethyl)phenyl]-1-(4-methylphenyl)-1H-pyrazole-4-carbonitrile

BUTTPARK 51\09-61

5-AMINO-1-P-TOLYL-1H-PYRAZOLE-4-CARBONITRILE

5-AMINO-1-(4-METHYLPHENYL)-1H-PYRAZOLE-4-CARBONITRILE

5-AMINO-4-CYANO-1-(4-METHYLPHENYL)PYRAZOLE

4-(5-Amino-4-cyano-1H-pyrazol-1-yl)toluene, 5-Amino-4-cyano-1-(4-methylphenyl)-1H-pyrazole

5-Amino-1-(p-tolyl)pyrazole-4-carbonitrile

1H-Pyrazole-4-carbonitrile, 5-amino-1-(4-methylphenyl)-

5-Amino-1-(4-methylphenyl)pyrazole-4-carbonitrile

5-amino-1-toluene-1h-pyrazole-4-methylnitrile

103646-82-8

C11H10N4