ChemicalBook > CAS DataBase List > 2,4,6-Trimethylphenol

2,4,6-Trimethylphenol

Product Name
2,4,6-Trimethylphenol
CAS No.
527-60-6
Chemical Name
2,4,6-Trimethylphenol
Synonyms
Phenol, 2,4,6-trimethyl-;MESITOL;mesito;HYDROXYMESITYLENE;2-hydroxymesitylen;2-Hydroxymesitylene;2,4,6-Trimethylpenol;2,4,6-Trimetylofenol;1,3,5-trimethylphenol;2,4,6-trimethyl-pheno
CBNumber
CB3682841
Molecular Formula
C9H12O
Formula Weight
136.19
MOL File
527-60-6.mol
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2,4,6-Trimethylphenol Property

Melting point:
70-72 °C(lit.)
Boiling point:
220 °C(lit.)
Density 
0.9809 (estimate)
vapor pressure 
3.86Pa at 25℃
FEMA 
4329 | 2,4,6-TRIMETHYLPHENOL
refractive index 
1.5148 (estimate)
Flash point:
220-221°C
storage temp. 
under inert gas (argon)
form 
Crystalline Needles
pka
pK1:10.88 (25°C)
color 
Beige
Odor
at 0.10 % in propylene glycol. mild phenolic coffee grounds
Odor Type
phenolic
Water Solubility 
1.008g/L(25 ºC)
JECFA Number
2013
BRN 
1859675
LogP
2.73 at 25℃
CAS DataBase Reference
527-60-6(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 2,4,6-trimethyl-(527-60-6)
EPA Substance Registry System
2,4,6-Trimethylphenol (527-60-6)
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Safety

Hazard Codes 
C,N
Risk Statements 
34-51/53
Safety Statements 
26-36/37/39-45-24/25-61
RIDADR 
UN 2430 8/PG 3
WGK Germany 
2
RTECS 
OX6590000
TSCA 
Yes
HazardClass 
8
PackingGroup 
III
HS Code 
29071990
Hazardous Substances Data
527-60-6(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T79006
Product name
2,4,6-Trimethylphenol
Purity
97%
Packaging
25g
Price
$124
Updated
2024/03/01
Sigma-Aldrich
Product number
53766
Product name
2,4,6-Trimethylphenol
Purity
certified reference material, TraceCERT
Packaging
100mg
Price
$124
Updated
2022/05/15
TCI Chemical
Product number
T0486
Product name
2,4,6-Trimethylphenol
Purity
>98.0%(GC)
Packaging
25g
Price
$148
Updated
2024/03/01
TCI Chemical
Product number
T0486
Product name
2,4,6-Trimethylphenol
Purity
>98.0%(GC)
Packaging
100g
Price
$443
Updated
2024/03/01
Alfa Aesar
Product number
A15041
Product name
2,4,6-Trimethylphenol, 98%
Packaging
100g
Price
$267
Updated
2024/03/01
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2,4,6-Trimethylphenol Chemical Properties,Usage,Production

Chemical Properties

BEIGE CRYSTALLINE NEEDLES

Production Methods

2,4,6-Trimethylphenol is the main product (more than 80%) of the gas phase alkylation of phenol with excess methanol (molar ratio 1 : 5) at 450 ℃ on magnesium oxide catalysts, which are doped with alkali or other metal oxides (e.g., V2O5, SrO). 2,6-Xylenol and 2,3,4,6-tetramethylphenol are the main byproducts.

Synthesis Reference(s)

Journal of the American Chemical Society, 107, p. 1060, 1985 DOI: 10.1021/ja00290a053
Synthetic Communications, 18, p. 1207, 1988 DOI: 10.1080/00397918808060912

Flammability and Explosibility

Not classified

Purification Methods

Crystallise the phenol from water and sublime it in vacuo. [Beilstein 6 IV 3253.]

2,4,6-Trimethylphenol Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4,6-Trimethylphenol Suppliers

Taizhou Tongxin Bio-Tech Co., Ltd
Tel
0523-18601685-898 18652728585
Email
sales@allyrise.com
Country
China
ProdList
2743
Advantage
60
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Nanjing Datang Chemical Co., Ltd
Tel
25-25-85431992 13951889906
Fax
+86-25-85287178
Email
vip@chemdatang.com
Country
China
ProdList
78
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17988
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
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View Lastest Price from 2,4,6-Trimethylphenol manufacturers

Chemwill Asia Co.,Ltd.
Product
2,4,6-Trimethylphenol 527-60-6 Mesitol 527-60-6
Price
US $5.86/KG
Min. Order
1KG
Purity
99.50% IN STOCK
Supply Ability
1500 MT per month
Release date
2019-08-23
Chemwill Asia Co.,Ltd.
Product
527-60-6 Mesitol 2,4,6-Trimethylphenol 527-60-6
Price
US $16.55/KG
Min. Order
1KG
Purity
99.50% IN STOCK
Supply Ability
1750 MT per month
Release date
2019-08-23
Chemwill Asia Co.,Ltd.
Product
2,4,6-Trimethylphenol 527-60-6
Price
US $2.55/KG
Min. Order
1KG
Purity
99.50% IN STOCK
Supply Ability
2600 MT per month
Release date
2019-08-23

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