2-BROMO-3-METHYL-2-BUTENE Property

Melting point:

-106.7°C (estimate)

Boiling point:

40 °C/75 mmHg (lit.)

Density 

1.284 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.474(lit.)

Flash point:

77 °F

storage temp. 

2-8°C(protect from light)

Safety

Hazard Codes 

Xn

Risk Statements 

10-22

Safety Statements 

36/37

RIDADR 

UN 1992 3/PG 3

WGK Germany 

3

HazardClass 

3.2

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H301Toxic if swalloed

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

2-BROMO-3-METHYL-2-BUTENE Chemical Properties,Usage,Production

Uses

2-Bromo-3-methyl-2-butene may be used in the preparation of:

• 2,3,4,5-tetramethyl-2,4-hexadiene
• 2-iodo-3-methyl-2-butene
• diastereomers of 2-amino-3-hydroxy-4,5-dimethylhexanoic acid
• lithium reagent, 2-lithio-3-methylbut-2-ene
• D-allo-(2R,3R,4R)-2-amino-3-hydroxy-4,5-dimethylhexanoic acid-containing peptide, pipecolidepsin A.

General Description

2-Bromo-3-methyl-2-butene is a vinylic bromide compound. Palladium/di-1-adamantyl-n-butylphosphine-catalyzed reductive carbonylation of 2-bromo-3-methyl-2-butene has been reported. Cross-coupling reaction of 2-bromo-3-methyl-2-butene with potassium 6-(benzoyloxy)hexyltrifluoroborate and 3-(benzoyloxy)propyltrifluoroborate has been investigated.