ChemicalBook > CAS DataBase List > 2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE

2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE

Product Name
2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE
CAS No.
303985-05-9
Chemical Name
2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE
Synonyms
BET-IN-7;2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE;5-Pyrimidinecarbonitrile, 2-[[(2-chlorophenyl)methyl]thio]-1,6-dihydro-6-oxo-4-phenyl-
CBNumber
CB3702437
Molecular Formula
C18H12ClN3OS
Formula Weight
353.83
MOL File
Mol file
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2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE Property

Boiling point:
512.9±60.0 °C(Predicted)
Density 
1.33±0.1 g/cm3(Predicted)
pka
4.66±0.50(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
HCH0078583
Product name
2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE
Purity
95.00%
Packaging
1MG
Price
$647.61
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0078583
Product name
2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE
Purity
95.00%
Packaging
10MG
Price
$679.14
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0078583
Product name
2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE
Purity
95.00%
Packaging
5MG
Price
$687.35
Updated
2021/12/16
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2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE Chemical Properties,Usage,Production

Uses

BET-IN-7 (Compound 1) is a potent inhibitor of BET with a Ki and Kd of 12.27 and 89.3 μM, respectively. BET-IN-7 has the potential for the research of sepsis[1].

References

[1] Chen X, et al. Discovery of 2-((2-methylbenzyl)thio)-6-oxo-4-(3,4,5-trimethoxyphenyl)-1,6-dihydropyrimidine-5-carbonitrile as a novel and effective bromodomain and extra-terminal (BET) inhibitor for the treatment of sepsis. Eur J Med Chem. 2022 May 8;238: DOI:10.1016/j.ejmech.2022.114423

2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE Suppliers

China 1 United Kingdom 1 United States 3 Global 5
TargetMol Chemicals Inc.
Tel
15002134094
Email
marketing@targetmol.cn
Country
China
ProdList
29357
Advantage
58
TargetMol Chemicals Inc.
Tel
+17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
19961
Advantage
58

303985-05-9, 2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILERelated Search:


  • 2-[(2-CHLOROBENZYL)SULFANYL]-4-HYDROXY-6-PHENYL-5-PYRIMIDINECARBONITRILE
  • 5-Pyrimidinecarbonitrile, 2-[[(2-chlorophenyl)methyl]thio]-1,6-dihydro-6-oxo-4-phenyl-
  • BET-IN-7
  • 303985-05-9