1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE
- Product Name
- 1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE
- CAS No.
- 57602-02-5
- Chemical Name
- 1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE
- Synonyms
- CAS_57602-02-5;Br-PEG4-bromide;Br-PEG4-CH2CH2Br;Br-(CH2CH2O)5-Br;Br-PEG4-br,Bromo-PEG4-bromide;1,2-Bis[2-(2-bromoethoxy)ethoxy]ethane;1,14-Dibro-3,6,9,12-tetraoxatetradecane;1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE;3,6,9,12-Tetraoxatetradecane, 1,14-dibromo-;Br-PEG4-CH2CH2Br/3,6,9,12-Tetraoxatetradecane, 1,14-dibromo-
- CBNumber
- CB3705418
- Molecular Formula
- C10H20Br2O4
- Formula Weight
- 364.07
- MOL File
- 57602-02-5.mol
1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE Property
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform
- form
- Clear Light Yellow Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D6458
- Product name
- 1,14-Dibromo-3,6,9,12-tetraoxatetradecane
- Purity
- min. 95.0 %
- Packaging
- 250MG
- Price
- $156
- Updated
- 2025/07/31
- Product number
- D6458
- Product name
- 1,14-Dibromo-3,6,9,12-tetraoxatetradecane
- Purity
- min. 95.0 %
- Packaging
- 1G
- Price
- $390
- Updated
- 2025/07/31
- Product number
- D425480
- Product name
- 1,14-Dibromo-3,6,9,12-tetraoxatetradecane
- Packaging
- 250mg
- Price
- $990
- Updated
- 2021/12/16
- Product number
- FD140884
- Product name
- 1,14-Dibromo-3,6,9,12-tetraoxatetradecane
- Packaging
- 100mg
- Price
- $84
- Updated
- 2021/12/16
- Product number
- FD140884
- Product name
- 1,14-Dibromo-3,6,9,12-tetraoxatetradecane
- Packaging
- 250mg
- Price
- $167.5
- Updated
- 2021/12/16
1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE Chemical Properties,Usage,Production
Description
Bromo-PEG4-bromide is a PEG linker containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Chemical Properties
Clear Light Yellow Liquid
Uses
A cross-linking reagent.
Synthesis
109789-39-1
57602-02-5
The general procedure for the synthesis of dibromopenta PEG from pentaethylene glycol disulfonate (CAS: 109789-39-1) is as follows: in Example 2, pentaethylene glycol disulfonate (3.94 g, 10 mmol) was dissolved with tetrabutylammonium bromide (13.3 g) in acetonitrile (50 mL). The reaction mixture was stirred for 16 h under the protection of nitrogen atmosphere. Upon completion of the reaction, the solvent was removed by distillation. Subsequently, liquid-liquid extraction was performed by adding ethyl acetate and water to the residue. The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated. Finally, the target product dibromopenta PEG (2.73 g, 75% yield) was purified by column chromatography. The structure of the product was confirmed by 1H-NMR (CDCl3): δ 3.49 (t, 4H), 3.69 (s, 12H), 3.84 (t, 4H).
IC 50
PEGs
References
[1] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 3, p. 557 - 560
[2] Steroids, 2006, vol. 71, # 10, p. 911 - 921
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 2, p. 636 - 643
[4] Patent: US2016/82117, 2016, A1. Location in patent: Paragraph 0046
1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE manufacturers
- Product
- 1,14-DIBROMO-3,6,9,12-TETRAOXATETRADECANE 57602-02-5
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-04-24
- Product
- Br-PEG4-Br 57602-02-5
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25
- Product
- 1,14-DibroMo-3,6,9,12-tetraoxatetradecane 57602-02-5
- Price
- US $1.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%+
- Supply Ability
- 100 tons
- Release date
- 2019-12-26