Dilauryl thiodipropionate Property

Melting point:

40-42 °C(lit.)

Boiling point:

570.34°C (rough estimate)

Density 

0.915 g/mL at 25 °C(lit.)

vapor pressure 

0.2 mm Hg ( 163 °C)

refractive index 

1.5220 (estimate)

Flash point:

>230 °F

storage temp. 

2-8°C

solubility 

Chloroform (Slightly), Isopropanol (Slightly, Heated)

form 

Solid

color 

White to Off-White

Specific Gravity

0.916

Odor

wh. flakes, sweetish odor

InChIKey

GHKOFFNLGXMVNJ-UHFFFAOYSA-N

LogP

11.916 (est)

CAS DataBase Reference

123-28-4(CAS DataBase Reference)

NIST Chemistry Reference

Propionic acid, 3,3'-thiodi-, didodecyl ester(123-28-4)

EPA Substance Registry System

Dilauryl 3,3'-thiodipropionate (123-28-4)

Safety

WGK Germany 

1

RTECS 

UF8000000

HS Code 

2930909165

Hazardous Substances Data

123-28-4(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Dilauryl thiodipropionate Chemical Properties,Usage,Production

Appearance

White to Almost white powder to crystal

Description

Dilauryl thiodipropionate (DLTDP) is a part synthetic, part plant-derived ester blend made from the fatty alcohol lauryl alcohol and the antioxidant thiodipropionic acid. Not surprisingly, it has antioxidant benefits on the skin and, according to older research from Avon, may play a role in fading the appearance of discolourations. It also works in cosmetics as a sequestering agent, which helps keep ingredients in a formula from having unwanted interactions. As such, it also helps stabilize cosmetics. DLTDP is a secondary artificial antioxidant widely used to extend the shelf life of products in the food, cosmetic, and polymer industries. Furthermore, some studies on asphalt antioxidants warned about the softening effect of DLTDP on asphalt binders, even after ageing. DLTDP has been declared by the U.S. Food and Drug Administration (FDA) as generally recognized as safe (GRAS) for use in food and cosmetics, which implies its safe use when used as intended and under specific limitations (based mainly on fat content)[1].

Uses

Didodecyl 3,3'-Thiodipropionate (dilauryl thiodipropionate) is an antioxidant used as a modifier to stabilize acrylonitrile-butadiene-styrene (ABS) graft copolymers due to a strong synergistic effect. This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

Uses

Dilauryl Thiodipropionate (DLTDP) is an antioxidant that exists as white crystalline flakes of sweetish ester-like odor. It is insoluble in water but soluble in inorganic solvents. It is used in fats and oils to prevent rancidity. It is used in food when the total antioxidant content is not over 0.02% of the fat or oil content.

Uses

Didodecyl 3,3''-Thiodipropionate is an antioxidant used as a modifier to stabilize acrylonitrile-?butadiene-?styrene (ABS) graft copolymers due to a strong synergistic effect.

Definition

ChEBI: Didodecyl thiobispropanoate is a dicarboxylic acid.

Flammability and Explosibility

Non flammable

Safety Profile

An eye irritant. When heated to decomposition it emits toxic fumes of SOx. Thiodipropionic Acid and Dilauryl Thiodipropionate are also on the list of substances that are Generally Recognized As Safe (GRAS ) as chemical preservatives for use in foods.

Toxicology

According to the classification scheme of Hodge and Sterner, thiodipropionic acid (TDPA) and Dilauryl thiodipropionate (DLTDP) were slightly toxic when administered to mice and rats by the oral route. TDPA, when administered intraperitoneally, was moderately toxic to rats, while DLTDP was slightly toxic. TDPA was moderately toxic when administered intravenously to mice. TDPA and DLTDP were considered relatively nontoxic in subchronic oral toxicity studies with rats. No specific treatment-related effects were noted when TDPA was administered in the drinking water to guinea pigs for 4 months. No irritation was produced by a makeup foundation containing 0.05% DLTDP when tested at 0.0025% on intact and abraded skin of New Zealand white rabbits. Neither TDPA nor DLTDP produced signs of irritation when applied to the shaved skin of rabbits for 24 hours. In a guinea pig maximisation test, a makeup foundation containing 0.05% DLTDP was not a sensitizer. TDPA was tested for sensitization potential in guinea pigs, and though there were signs of local irritation at the injection sites, the TDPA was not considered a sensitizer. DLTDP was not phototoxic to New Zealand white rabbits at a concentration of 0.05% in a makeup foundation. No signs of irritation were observed when a solution containing TDPA was placed into the conjunctival sacs of rabbits. TDPA was neither a teratogen nor a reproductive toxicant when administered orally to mice, rats, hamsters, or rabbits during gestation.

References

[1] I. Camargo. “Dilauryl thiodipropionate as a regeneration agent for reclaimed asphalts.” Construction and Building Materials (2023).