ChemicalBook > CAS DataBase List > ROBINETIN

ROBINETIN

Product Name
ROBINETIN
CAS No.
490-31-3
Chemical Name
ROBINETIN
Synonyms
ROBINETIN;norkanugin;Robinetin-RM;5-HYDROXYFISETIN;5-HYDROXYFISETIN hplc;Robinetin, 10 mM in DMSO;3,3’,4’,5’,7-pentahydroxy-flavon;3,7,3',4',5'-PENTAHYDROXYFLAVONE;3,3',4',5',7-Pentahydroxyflavone;3,7,3'',4'',5''-PENTAHYDROXYFLAVONE WITH HPLC
CBNumber
CB3740354
Molecular Formula
C15H10O7
Formula Weight
302.24
MOL File
490-31-3.mol
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ROBINETIN Property

Melting point:
326-328°C
Boiling point:
363.28°C (rough estimate)
Density 
1.3616 (rough estimate)
refractive index 
1.4790 (estimate)
storage temp. 
2-8°C
solubility 
DMSO (Sparingly), Methanol (Slightly, Heated)
form 
Solid
pka
6.82±0.40(Predicted)
color 
Yellow to Dark Yellow
LogP
2.550 (est)
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Safety

Risk Statements 
22
Safety Statements 
22-45
RIDADR 
2811
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
R639515
Product name
Robinetin
Packaging
10mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FR36383
Product name
Robinetin
Packaging
25mg
Price
$85
Updated
2021/12/16
ChemScene
Product number
CS-0016755
Product name
Robinetin
Purity
≥97.0%
Packaging
5mg
Price
$295
Updated
2021/12/16
Biosynth Carbosynth
Product number
FR36383
Product name
Robinetin
Packaging
250mg
Price
$425
Updated
2021/12/16
Matrix Scientific
Product number
098518
Product name
3,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
Purity
95+%
Packaging
1g
Price
$588
Updated
2021/12/16
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ROBINETIN Chemical Properties,Usage,Production

Uses

Robinetin (3,3',4',5',7-Pentahydroxyflavone), a naturally occurring flavonoid with remarkable ‘two color’ intrinsic fluorescence properties, has antifungal, antiviral, antibacterial, antimutagenesis, and antioxidant activity. Robinetin also can inhibit lipid peroxidation and protein glycosylation[1][2][3][4][5].

Definition

ChEBI: A pentahydroxyflavone that is flavone substituted by hydroxy groups at positions 3, 7, 3, 4' and 5'.

References

[1] Fesen MR, et, al. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem Pharmacol. 1994 Aug 3;48(3):595-608. DOI:10.1016/0006-2952(94)90291-7
[2] Cushnie TPT, et, al. Antimicrobial activity of flavonoids. Int J Antimicrob Agents. 2005 Nov;26(5):343-56. DOI:10.1016/j.ijantimicag.2005.09.002
[3] Chaudhuri S, et, al. Binding of the bioflavonoid robinetin with model membranes and hemoglobin: Inhibition of lipid peroxidation and protein glycosylation. J Photochem Photobiol B. 2010 Jan 21;98(1):12-9. DOI:10.1016/j.jphotobiol.2009.10.002
[4] Birt DF, et, al. Anti-mutagenesis and anti-promotion by apigenin, robinetin and indole-3-carbinol. Carcinogenesis. 1986 Jun;7(6):959-63. DOI:10.1093/carcin/7.6.959
[5] Manrique-de-la-Cuba MF, et, al. Theoretical study of the antioxidant capacity of the flavonoids present in the Annona muricata (Soursop) leaves. J Mol Model. 2019 Jun 25;25(7):200. DOI:10.1007/s00894-019-4083-7

ROBINETIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ROBINETIN manufacturers

Career Henan Chemical Co
Product
ROBINETIN 490-31-3
Price
US $1.00/kg
Min. Order
1 mg
Purity
99%
Supply Ability
100KG
Release date
2018-12-25

490-31-3, ROBINETINRelated Search:


  • ROBINETIN
  • 3,3’,4’,5’,7-pentahydroxy-flavon
  • 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on
  • norkanugin
  • 3,7,3',4',5'-PENTAHYDROXYFLAVONE
  • 5-HYDROXYFISETIN
  • 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4-benzopyrone
  • 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl-4H-1-benzopyran-4-one) (Robinetin)
  • 3,7,3'',4'',5''-PENTAHYDROXYFLAVONE WITH HPLC
  • 5-HYDROXYFISETIN hplc
  • 3,7-Dihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one
  • 4H-1-Benzopyran-4-one, 3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)
  • Inhibitor,antibacterial,antioxidant,Robinetin,flavonoid,Bacterial,antiviral,peroxidation,antifungal,protein,inhibit,antimutagenesis,glycosylation,Fungal,lipid,HIV Integrase
  • 3,3',4',5',7-Pentahydroxyflavone
  • Robinetin-RM
  • Robinetin, 10 mM in DMSO
  • 490-31-3
  • Flavanols
  • Penta-substituted Flavones