(S)-BEL

Product Name: (S)-BEL
CAS No.: 478288-94-7
Chemical Name: (S)-BEL
Synonyms: (S)-BEL;(S)-BROMOENOL LACTONE;(S)-Bromoenol lactone(solution in acetate);(3S,6E)-6-(bromomethylidene)-3-naphthalen-1-yloxan-2-one;6E-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPHTHALENYL)-2H-PYRAN-2-ONE;2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-, (3S,6E)-
CBNumber: CB3748350
Molecular Formula: C16H13BrO2
Formula Weight: 317.18
MOL File: Mol file

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(S)-BEL Property

Boiling point:: 467.0±45.0 °C(Predicted)
Density: 1.538±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C, protect from light
solubility: DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 5 mg/ml; PBS (pH 7.2): .05 mg/ml
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10006801
Product name: (S)-Bromoenol lactone
Purity: ≥98%
Packaging: 500μg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 10006801
Product name: (S)-Bromoenol lactone
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 10006801
Product name: (S)-Bromoenol lactone
Purity: ≥98%
Packaging: 5mg
Price: $230
Updated: 2024/03/01

Cayman Chemical

Product number: 10006801
Product name: (S)-Bromoenol lactone
Purity: ≥98%
Packaging: 10mg
Price: $365
Updated: 2024/03/01

AK Scientific

Product number: 1098AH
Product name: (S)-Bromoenollactone
Packaging: 5mg
Price: $353
Updated: 2021/12/16

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(S)-BEL Chemical Properties,Usage,Production

Uses

(S)-Bromoenol lactone ((S)-BEL) is an irreversible, chiral, mechanism-based inhibitor of calcium-independent phospholipase A2β (iPLA2β) that inhibits the vasopressin-induced release of arachidonate from cultured rat aortic smooth muscle (A10) cells with an IC50 of 2 μM[1].

Definition

ChEBI: (S)-Bromoenol lactone is a member of naphthalenes.

IC 50

PLA2

References

[1] Jenkins CM, et al. Identification of calcium-independent phospholipase A2 (iPLA2) beta, and not iPLA2gamma, as the mediator of arginine vasopressin-induced arachidonic acid release in A-10 smooth muscle cells. Enantioselective mechanism-based discriminati DOI:10.1074/jbc.M202568200

(S)-BEL Preparation Products And Raw materials

Raw materials

Preparation Products

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(S)-BEL Suppliers

China 15 United States 2 Global 17

BOC Sciences

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478288-94-7, (S)-BELRelated Search:

BROMOENOL LACTONE

(S)-BEL

(3S,6E)-6-(bromomethylidene)-3-naphthalen-1-yloxan-2-one

(S)-BROMOENOL LACTONE

6E-(BROMOMETHYLENE)TETRAHYDRO-3-(1-NAPHTHALENYL)-2H-PYRAN-2-ONE

2H-Pyran-2-one, 6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-, (3S,6E)-

(S)-Bromoenol lactone(solution in acetate)

478288-94-7