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2,3-DINOR PROSTAGLANDIN E1

Product Name
2,3-DINOR PROSTAGLANDIN E1
CAS No.
7046-40-4
Chemical Name
2,3-DINOR PROSTAGLANDIN E1
Synonyms
2,3-dinor PGE1;2,3-DINOR PROSTAGLANDIN E1;2,3-dinor Prostaglandin E?;GTUGBRJEKVKOKQ-LRSAKWJDSA-N;2,3-dinor Prostaglandin E1;9-oxo-11α,15S-dihydroxy-2,3-dinor-prost-13E-en-1-oic acid;9-OXO-11ALPHA,15S-DIHYDROXY-2,3-DINOR-PROST-13E-EN-1-OIC ACID;Cyclopentanepentanoic acid, 3-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-5-oxo-, (1R,2R,3R)-
CBNumber
CB3749665
Molecular Formula
C18H30O5
Formula Weight
326.43
MOL File
7046-40-4.mol
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2,3-DINOR PROSTAGLANDIN E1 Property

Boiling point:
508.6±50.0 °C(Predicted)
Density 
1.164±0.06 g/cm3(Predicted)
solubility 
DMF: >100 mg/ml; DMSO: >50 mg/ml; Ethanol: >50 mg/ml; PBS (pH 7.2): 1.67 mg/ml
pka
4.75±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
13120
Product name
2,3-dinor Prostaglandin E1
Purity
≥98%
Packaging
25μg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
13120
Product name
2,3-dinor Prostaglandin E1
Purity
≥98%
Packaging
50μg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
13120
Product name
2,3-dinor Prostaglandin E1
Purity
≥98%
Packaging
100μg
Price
$198
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CCH0006022
Product name
2,3-DINOR PROSTAGLANDIN E1
Purity
95.00%
Packaging
5MG
Price
$504.16
Updated
2021/12/16
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2,3-DINOR PROSTAGLANDIN E1 Chemical Properties,Usage,Production

Description

Prostaglandin E1 (PGE1) is not a major naturally occurring prostaglandin, but it is widely administered clinically for several indications including peripheral occlusive vascular disease, erectile dysfunction and in neonatal cardiology.1,2 The metabolism of PGE1 is normally initiated by oxidation at C-15, resulting in 13,14-dihydro-15-keto PGE1 as the major metabolite. However, inhibition of this pathway or saturation by excess substrate could theoretically lead to enhanced production of 2,3-dinor metabolites, including 2,3-dinor PGE1. The biological activity of 2,3-dinor PGE1 has not been published. Cayman Chemical is a leading supplier of prostaglandins and their metabolites, and is currently the exclusive manufacturer of 2,3-dinor PGE1.

Definition

ChEBI: 2,3-Dinor-PGE1 is a prostanoid.

References

1. Virag, R., Shoukry, K., Floresco, J., et al. Intracavernous self-injection of vasoactive drugs in the treatment of impotence: 8-Year experience with 615 cases J. Urol. 145(2),287-293(1991).
2. Hoshi, K. Approved indications of lipo-PGE1 in Japan Adv. Drug Deliv. Rev. 20(2-3),171-176(1996).

2,3-DINOR PROSTAGLANDIN E1 Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-DINOR PROSTAGLANDIN E1 Suppliers

ChemStrong Scientific Co.,Ltd
Tel
0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55717
Advantage
58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd
Tel
0571-85361029
Fax
0571-85361029
Email
synstar518@163.com
Country
China
ProdList
1991
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
8740
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48617
Advantage
58
Aladdin Scientific
Tel
+1-833-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57511
Advantage
58

7046-40-4, 2,3-DINOR PROSTAGLANDIN E1Related Search:


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  • GTUGBRJEKVKOKQ-LRSAKWJDSA-N
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  • 2,3-dinor PGE1
  • 2,3-DINOR PROSTAGLANDIN E1
  • Cyclopentanepentanoic acid, 3-hydroxy-2-[(1E,3S)-3-hydroxy-1-octen-1-yl]-5-oxo-, (1R,2R,3R)-
  • 2,3-dinor Prostaglandin E?
  • 7046-40-4