ChemicalBook > CAS DataBase List > HEXANOIC ANHYDRIDE

HEXANOIC ANHYDRIDE

Product Name
HEXANOIC ANHYDRIDE
CAS No.
2051-49-2
Chemical Name
HEXANOIC ANHYDRIDE
Synonyms
N-HEXANOIC ANHYDRIDE;CAPROIC ANHYDRIDE;hexanoylhexanoate;N-HEXOIC ANHYDRIDE;Capronic anhydride;Hexanoyl anhydride;n-Capriocanhydride;HEXANOIC ANHYDRIDE;N-CAPROIC ANHYDRIDE;N-CAPRONIC ANHYDRIDE
CBNumber
CB3766110
Molecular Formula
C12H22O3
Formula Weight
214.3
MOL File
2051-49-2.mol
More
Less

HEXANOIC ANHYDRIDE Property

Melting point:
-40 °C
Boiling point:
246-248 °C (lit.)
Density 
0.928 g/mL at 20 °C (lit.)
vapor pressure 
2.9Pa at 25℃
refractive index 
n20/D 1.428(lit.)
Flash point:
>230 °F
storage temp. 
Store below +30°C.
solubility 
ethanol: soluble1g/10 mL, clear, colorless
form 
Liquid
color 
Clear colorless to light yellow
explosive limit
0.7%(V)
Water Solubility 
Hydrolyzes in water.
Sensitive 
Moisture Sensitive
BRN 
1776561
InChI
1S/C12H22O3/c1-3-5-7-9-11(13)15-12(14)10-8-6-4-2/h3-10H2,1-2H3
InChIKey
PKHMTIRCAFTBDS-UHFFFAOYSA-N
SMILES
CCCCCC(=O)OC(=O)CCCCC
LogP
4.45 at 25℃
CAS DataBase Reference
2051-49-2(CAS DataBase Reference)
EPA Substance Registry System
Hexanoic acid, anhydride (2051-49-2)
More
Less

Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
TSCA 
TSCA listed
HazardClass 
8
PackingGroup 
III
HS Code 
29159000
Storage Class
8A - Combustible corrosive hazardous materials
Hazard Classifications
Skin Corr. 1B
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
194530
Product name
Hexanoic anhydride
Purity
97%
Packaging
50g
Price
$46.17
Updated
2025/07/31
Sigma-Aldrich
Product number
21580
Product name
Hexanoic anhydride
Purity
purum, ≥97.0% (GC)
Packaging
250ML
Price
$73.3
Updated
2025/07/31
Sigma-Aldrich
Product number
194530
Product name
Hexanoic anhydride
Purity
97%
Packaging
250g
Price
$94.8
Updated
2025/07/31
Sigma-Aldrich
Product number
21580
Product name
Hexanoic anhydride
Purity
purum, ≥97.0% (GC)
Packaging
50mL
Price
$33
Updated
2023/06/20
TCI Chemical
Product number
C0021
Product name
Hexanoic Anhydride
Purity
>96.0%(GC)
Packaging
25mL
Price
$18
Updated
2025/07/31
More
Less

HEXANOIC ANHYDRIDE Chemical Properties,Usage,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

Hexanoic anhydride has been used in:

  • green synthesis of esters of acyclovir (acyclovir prodrugs)
  • preparation of hexanoyl-modified chitosan nanoparticles and chitosan-based polymeric surfactants via N-acylation of chitosans

Uses

Hexanoic anhydride was used in:

  • green synthesis of esters of acyclovir (acyclovir prodrugs)
  • preparation of hexanoyl-modified chitosan nanoparticles
  • preparation of chitosan-based polymeric surfactants via N-acylation of chitosans

Uses

Hexanoic Anhydride, is used as a reactant in the total synthesis of acremomannolipin A via steroselective β-mannosylation of 4,6,-O-benzylidene-protected mannosyl sulfoxide with a D-mannitol derivative.

Preparation

To an ice-cooled flask containing 116 gm (1.0 mole) of n-caproic acid is added 21.0-23.10 gm (0.5-0.55 mole) of ketene at a rate of 0.45 mole/hr. The reaction mixture is fractionally distilled at atmospheric pressure to afford a forecut of acetone, acetic acid, and acetic anhydride. The oil bath is raised to 220°C over a 1-hr period, kept there for 3 hr to ensure complete removal of acetic acid, and then cooled. The distillation is continued under reduced pressure to afford 86-95 gm (80-87%), b.p. 109- 112°C (3 mm Hg) and b.p. 118-121°C (6 mm Hg).

Flammability and Explosibility

Not classified

HEXANOIC ANHYDRIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

HEXANOIC ANHYDRIDE Suppliers

Changzhou KOYE Chemical Co.,LTD.
Tel
519-81882581 18602584369
Email
Lydia@kwchem.com
Country
China
ProdList
102
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Beijing HwrkChemical Technology Co., Ltd
Tel
010-89508211 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9401
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
More
Less

View Lastest Price from HEXANOIC ANHYDRIDE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Hexanoic anhydride 2051-49-2
Price
US $0.00-0.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25
Shaanxi Dideu New Materials Co. Ltd
Product
HEXANOIC ANHYDRIDE 2051-49-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2024-11-19
Hebei Chuanghai Biotechnology Co,.LTD
Product
Hexanoic Anhydride 2051-49-2
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-15

2051-49-2, HEXANOIC ANHYDRIDERelated Search:


  • N-BUTYLACETIC ANHYDRIDE
  • N-CAPRONIC ANHYDRIDE
  • N-CAPROIC ANHYDRIDE
  • N-HEXANOIC ANHYDRIDE
  • N-HEXOIC ANHYDRIDE
  • PENTYLFORMIC ANHYDRIDE
  • N-CAPROICANHYDRIDE=HEXANOICANHYDRIDE
  • Bis(hexanoic)anhydride
  • Biscaproic anhydride
  • Bishexanoic anhydride
  • Dihexanoic anhydride
  • Hexanoic anhydride,97%
  • Hexanoic anhydride, 97% 250GR
  • Hexanoic anhydride, 97% 50GR
  • Hexanoic acid,1,1'-anhydride
  • Hexanoic anhydride 97%
  • Caproic acid anhydride
  • Capronic acid anhydride
  • Capronic anhydride
  • hexanoicacid,anhydride
  • Hexanoicacidanhydride
  • Hexanoyl anhydride
  • n-Capriocanhydride
  • n-Hexanoic acid anhydride
  • HEXANOIC ANHYDRIDE
  • CAPROIC ANHYDRIDE
  • 6-benzamido-2-bromohexanoic acid
  • Hexanoic Anhydride &gt
  • hexanoylhexanoate
  • HEXANOIC ANHYDRIDE ISO 9001:2015 REACH
  • High Quality HEXANOIC ANHYDRIDE CAS 2051-49-2 with Free sample
  • 2051-49-2
  • C12H22O3
  • CH3CH24CO2O
  • C5H11CO2O
  • Carboxylic Acid Anhydrides
  • Carbonyl Compounds
  • Building Blocks
  • Organic Building Blocks
  • Pharmaceutical Intermediates