AC-IEPD-CHO

Product Name: AC-IEPD-CHO
CAS No.: 352520-90-2
Chemical Name: AC-IEPD-CHO
Synonyms: AC-IEPD-CHO;AC-ILE-GLU-PRO-ASP-CHO;CASPASE-8 INHIBITOR III;GRANZYME B INHIBITOR IV;N-Acetyl-Ile-Glu-Pro-Asp-al;AC-ILE-GLU-PRO-ASP-ALDEHYDE;AC-ILE-GLU-PRO-ASP-ALDEHYDE (PSEUDO ACID)
CBNumber: CB3771451
Molecular Formula: C22H34N4O9
Formula Weight: 498.53
MOL File: Mol file

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AC-IEPD-CHO Property

storage temp.: -15°C
solubility: DMSO: 5mg/mL
form: Lyophilized Powder
color: White to off-white
Sequence: Ac-Ile-Glu-Pro-Asp-CHO

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 368056
Product name: Granzyme B Inhibitor IV
Purity: The Granzyme B Inhibitor IV controls the biological activity of Granzyme B. This small molecule/inhibitor is primarily used for Cancer applications.
Packaging: 1MG
Price: $163
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: PEP0005524
Product name: AC-IEPD-CHO
Purity: 95.00%
Packaging: 5MG
Price: $502.58
Updated: 2021/12/16

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AC-IEPD-CHO Chemical Properties,Usage,Production

Uses

Ac-IEPD-CHO is a reversible granzyme B inhibitor with a Ki of 80 nM[1]. Ac-IEPD-CHO is also a caspase-8 inhibitor[2].

Biological Activity

Cell permeable: no', 'Primary Target
granzyme B', 'Product does not compete with ATP.', 'Reversible: yes

References

[1] Mi-Sun Kim, et al. Approaches to design non-covalent inhibitors for human granzyme B (hGrB). Org Biomol Chem. 2014 Nov 28;12(44):8952-65. DOI:10.1039/c4ob01874e
[2] In-Sun Hong, et al. Gonadotropin-releasing hormones I and II induce apoptosis in human granulosa cells. J Clin Endocrinol Metab. 2008 Aug;93(8):3179-85. DOI:10.1210/jc.2008-0127
[3] Jamann H, et al. Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes. Front Immunol. 2022 Apr 11;13:850616. DOI:10.3389/fimmu.2022.850616

AC-IEPD-CHO Preparation Products And Raw materials

Raw materials

Preparation Products

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AC-IEPD-CHO Suppliers

China 23 United Kingdom 1 United States 4 Global 28

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352520-90-2, AC-IEPD-CHORelated Search:

AC-IEPD-CHO

AC-ILE-GLU-PRO-ASP-ALDEHYDE

AC-ILE-GLU-PRO-ASP-ALDEHYDE (PSEUDO ACID)

AC-ILE-GLU-PRO-ASP-CHO

GRANZYME B INHIBITOR IV

CASPASE-8 INHIBITOR III

N-Acetyl-Ile-Glu-Pro-Asp-al

352520-90-2